The Best Slay the Spire Cards Tier List

S

A

B

C

D

F

S Tier

Apotheosis, Biased Cognition, Echo Form, Alchemize, Feed, Offering, Seek, Lesson Learned, Well-Laid Plans, Scrawl, Adrenaline, Wraith Form, Vault, Immolate, Corruption

A Tier

Fission, Defragment, Genetic Algorithm, Electrodynamics, Dark Shackles, Hand of Greed, Tantrum, Malaise, Disarm, After Image, Glacier, Catalyst, Talk to the Hand, Acrobatics, Master of Strategy, Impervious, Self Repair, Skim, Feel No Pain, Rushdown, Piercing Wail, Hologram, Battle Trance, Meditate, Dark Embrace, Shrug It Off, Corpse Explosion, Core Surge, Wallop, Reaper, Cut Through Fate, Buffer, Fear No Evil, Footwork, Secret Technique, Calculated Gamble, Thinking Ahead, Shockwave, Terror, Omniscience, Inner Peace, Backflip, Doom and Gloom, Mental Fortress, Indignation, Bloodletting, Wheel Kick, Empty Fist, Trip, Tactician, Panacea, Coolheaded, Pommel Strike, Blade Dance, Glass Knife, Violence, Equilibrium, Secret Weapon, Aggregate, Inflame, Chill

B Tier

Recycle, Barricade, Flame Barrier, Leg Sweep, Burst, Foresight, Die Die Die, Spot Weakness, Tools of the Trade, Reinforced Body, Halt, Nightmare, Deus Ex Machina, Capacitor, Ball Lightning, Uppercut, Burning Pact, Cold Snap, Flurry of Blows, Brutality, Fiend Fire, Reboot, True Grit, Dagger Throw, Blasphemy, Machine Learning, Backstab, Third Eye, Compile Driver, White Noise, Brilliance, Escape Plan, Phantasmal Killer, Noxious Fumes, Carnage, Crescendo, Exhume, Bouncing Flask, Go for the Eyes, Devotion, Ghostly Armor, Crippling Cloud, Darkness, Charge Battery, Headbutt, TURBO, Impatience, Deceive Reality, Beam Cell, Empty Mind, Wish, Predator, Panic Button, Sunder, Second Wind, Prostrate, Eviscerate, Sweeping Beam, Seeing Red, Dash, Demon Form, Crush Joints, Creative AI, Rainbow, Hyperbeam, Reflex, Limit Break, Consecrate, Sanctity, Deep Breath, FTL, Dropkick, Blind, Blur, Rebound

C Tier

Bullet Time, Wave of the Hand, Establishment, Armaments, Anger, Whirlwind, Evolve, Tranquility, Heatsinks, Finesse, Bowling Bash, Sands of Time, Blood for Blood, Flash of Steel, Deadly Poison, Good Instincts, Ragnarok, Accuracy, Discovery, Poisoned Stab, Power Through, Boot Sequence, Foreign Influence, Body Slam, Sneaky Strike, Follow-Up, Pummel, All for One, Judgment, Bludgeon, Prepared, Hemokinesis, Flying Knee, Loop, Amplify, Conclude, Combust, All-Out Attack, Dramatic Entrance, Empty Body, Dagger Spray, Clothesline, Sword Boomerang, Intimidate, Entrench, Sash Whip, Heavy Blade, Melter, Spirit Shield, Just Lucky, Weave, Deflect, Carve Reality, Sentinel, Sucker Punch, Cloak and Dagger, Doppelganger, Twin Strike, Bandage Up, Endless Agony, Worship, Chaos, Steam Barrier, Sadistic Nature, Barrage, Recursion, Dual Wield, Force Field, Caltrops, Juggernaut, Cleave, Fasting, Envenom, Slice, Streamline, Flechettes, Like Water, A Thousand Cuts

D Tier

Purity, Battle Hymn, Deva Form, Reckless Charge, Rupture, Windmill Strike, Madness, Dodge and Roll, Transmutation, Consume, Overclock, Rip and Tear, Skewer, Havoc, Expertise, Simmering Fury, The Bomb, Collect, Finisher, Evaluate, Storm of Steel, Auto-Shields, Tempest, Swivel, Concentrate, Unload, Reach Heaven, Panache, Quick Slash, Blizzard, Berserk, Static Discharge, Fusion, Metallicize, Warcry, Multi-Cast, Meteor Strike, Masterful Stab, Perfected Strike, Bullseye, Metamorphosis, Double Energy, Chrysalis, Hello World, Fire Breathing, Thunderclap, Swift Strike, Bane, Stack, Double Tap, Pray, Storm, Infinite Blades, Enlightenment, Leap, Flying Sleeves, Study, Flex, Protect, Scrape, Rage, Magnetism, Alpha, Infernal Blade, Mayhem, Rampage, Iron Wave, Outmaneuver, Thunder Strike, Claw, Grand Finale, Choke, Setup, Nirvana, Wild Strike, Reprogram, Sever Soul, Riddle with Holes, Signature Move

F Tier

Heel Hook, Searing Blow, Mind Blast, Perseverance, Forethought, Jack of All Trades, Clash, Master Reality, Wreath of Flame, Distraction, Conjure Blade, Pressure Points