The Best Slay the Spire Cards Tier List

S

A

B

C

D

F

S Tier

Seek, Apotheosis, Offering

A Tier

Adrenaline, Wraith Form, Defragment, Well-Laid Plans, Self Repair, Echo Form, Scrawl, Genetic Algorithm, Core Surge, Feed, Corruption, Rushdown, Biased Cognition, Alchemize, After Image, Immolate, Inner Peace, Fear No Evil, Calculated Gamble, Footwork, Terror, Dark Shackles, Malaise, Blade Dance, Equilibrium, Reaper, Mental Fortress, Hand of Greed, Electrodynamics, Tantrum, Master of Strategy, Corpse Explosion, Fission, Battle Trance, Omniscience, Skim, Glacier, Catalyst, Feel No Pain, Vault, Cut Through Fate, Coolheaded, Piercing Wail, Pommel Strike, Reboot, Glass Knife, Lesson Learned, Shrug It Off, Doom and Gloom, Wheel Kick, Impervious, Acrobatics, Dark Embrace, Chill, Buffer

B Tier

Whirlwind, Backflip, Hologram, Flame Barrier, Inflame, Disarm, Burst, Talk to the Hand, Tools of the Trade, Ball Lightning, Die Die Die, Shockwave, Wallop, Loop, Reinforced Body, Cold Snap, Spot Weakness, Fiend Fire, Meditate, Burning Pact, Empty Fist, Uppercut, Nightmare, Panacea, Compile Driver, Leg Sweep, Seeing Red, Dash, Second Wind, Predator, Trip, Deceive Reality, Bouncing Flask, Backstab, Sunder, Crippling Cloud, Noxious Fumes, Brutality, Tactician, Brilliance, Blur, Dropkick, Third Eye, Rainbow, Limit Break, Phantasmal Killer, Power Through, Exhume, Follow-Up, Pummel, Indignation, True Grit, Capacitor, Secret Weapon, Recycle, TURBO, Carnage, Secret Technique, Go for the Eyes, Anger, Foresight

C Tier

Sweeping Beam, Violence, Hyperbeam, Deus Ex Machina, Evolve, Dramatic Entrance, Eviscerate, Charge Battery, Panache, Aggregate, Dagger Throw, Blasphemy, Blood for Blood, Escape Plan, Accuracy, Crescendo, Empty Body, White Noise, Rebound, Blind, Barricade, Prepared, Tranquility, Thinking Ahead, Flurry of Blows, Combust, Bloodletting, Sword Boomerang, Sneaky Strike, Empty Mind, Halt, Flash of Steel, Consume, Bullet Time, Boot Sequence, Purity, Headbutt, Ragnarok, Armaments, Finesse, Sands of Time, Demon Form, Bandage Up, Deadly Poison, Devotion, Twin Strike, Wish, Conclude, Cloak and Dagger, Dodge and Roll, Ghostly Armor, Spirit Shield, Establishment, Prostrate, Meteor Strike, Finisher, Hemokinesis, Darkness, Dagger Spray, All for One, Panic Button, Wave of the Hand, Fire Breathing, FTL, Infernal Blade, Doppelganger, Carve Reality, Bowling Bash, All-Out Attack, Intimidate, Mayhem, Reflex, A Thousand Cuts, Dual Wield, Double Tap, Rip and Tear, Foreign Influence, Consecrate, Beam Cell, Metallicize, Sanctity, Protect, Judgment, Heatsinks, Creative AI, Steam Barrier, Multi-Cast, Like Water, Sash Whip, Clothesline, Endless Agony, Evaluate, Crush Joints, Envenom, Leap, Simmering Fury, Double Energy, Unload, Wild Strike, Melter, Sadistic Nature, Pray, Skewer, Flying Knee

D Tier

Poisoned Stab, Auto-Shields, Sucker Punch, Deva Form, Weave, Bludgeon, Quick Slash, Streamline, Heavy Blade, Berserk, Machine Learning, Deflect, Chaos, Cleave, Just Lucky, Metamorphosis, Body Slam, Impatience, Flex, Juggernaut, Thunderclap, Windmill Strike, Rupture, Amplify, Bullseye, Flechettes, Swift Strike, Barrage, Tempest, Overclock, Static Discharge, Masterful Stab, Perseverance, Reach Heaven, Good Instincts, Claw, Enlightenment, Expertise, Caltrops, Sentinel, Master Reality, Recursion, Slice, The Bomb, Storm of Steel, Signature Move, Reckless Charge, Concentrate, Rampage, Perfected Strike, Havoc, Iron Wave, Deep Breath, Study, Rage, Sever Soul, Force Field, Hello World, Flying Sleeves, Madness, Nirvana, Fasting, Collect, Battle Hymn, Warcry, Blizzard, Infinite Blades, Chrysalis, Thunder Strike, Scrape, Entrench, Storm, Forethought, Discovery, Reprogram, Worship, Swivel, Heel Hook, Mind Blast, Riddle with Holes, Searing Blow, Jack of All Trades

F Tier

Choke, Alpha, Bane, Setup, Grand Finale, Outmaneuver, Magnetism, Conjure Blade, Transmutation, Wreath of Flame, Pressure Points, Stack, Fusion, Clash, Distraction