The Best Boss Relics Tier List

A list of all Slay the Spire boss relics, ranked from best to worst. We combined votes from 11 players to create this list. You have the opportunity to pick up to two boss relics per run. Boss relics tend to be very impacftul in shaping how your run will turn out. Each comes with an upside, but many also have a downside, which can be minor or crippling. It's very important to pick the right boss relic for your deck. This list will help you get an idea of which ones to go for and which to avoid.