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The Siren
The Binding of Isaac: Rebirth
Enemy
4 Total Votes
Tags
Chapter 3.5
Boss
Type
Boss
Location
Chapter 3.5
Rankings
81st
/ 102
The Hardest Binding of Isaac Bosses
3
25
Rating
Tier
10.3
Spread
3
25
Rating
Tier
10.3
Spread
3rd
/ 5
The Hardest Chapter 3.5 Bosses
2
14
Rating
Tier
20.2
Spread
2
14
Rating
Tier
20.2
Spread
