A list of all items from The Binding of Isaac: Rebirth, ranked from best to worst. We combined votes from 58 players to create this list. Based on the latest version of The Binding of Isaac: Repentance.
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Death Certificate, Glitched Crown, Sacred Heart
Red Key, Spoon Bender, More Options, Twisted Pair, Mom's Knife, The Mind, The D6, Spindown Dice, Holy Mantle, C Section, Tech X, Sacred Orb, Godhead, R Key, Blood Clot, A Lump of Coal, A Dollar, D Infinity, Eternal D6, Suplex!, Goat Head, Mutant Spider, Big Fan, Jacob's Ladder, Ghost Pepper, Book of Virtues, Spider Mod, Chaos, Cain's Other Eye, Crack the Sky, Genesis, Head of the Keeper, Smelter, Lemegeton, Yum Heart, Blue Map, Little Horn (Item), Blood of the Martyr, Lodestone, The Swarm, Mom's Ring, Papa Fly, Abaddon, Crooked Penny
Blank Card, Tooth Picks, Spirit Shackles, Angelic Prism, D7, Member Card, Sausage, Cricket's Body, The Virus, Isaac's Tomb, Metal Plate, Treasure Map, Keeper's Box, Bogo Bombs, Athame, Eye of Belial, Contract From Below, Red Stew, The Mark, A Pony, Monstro's Lung, Scorpio, Eve's Mascara, Duality, Ocular Rift, Spirit Sword, Bird Cage, My Little Unicorn, Divine Intervention, Book of Revelations, Contagion, The Parasite, Eye of the Occult, Trisagion, Bomber Boy, Binge Eater, Revelation, Pyromaniac, The Wafer, Euthanasia, Cricket's Head, Brimstone, Mystery Sack, Death's Touch, Crown of Light, Tarot Cloth, Mysterious Liquid, Dark Arts, Inner Child, Psy Fly, The Pact, Neptunus, Deep Pockets, Magic Mushroom, Incubus, MEAT!, Mega Mush, Stop Watch, Ball of Bandages, Mystery Egg, Money = Power, Odd Mushroom (Thin), Sulfur, Larynx, Flip, Book of the Dead, The Small Rock, A Bar of Soap, Guppy's Head, Analog Stick, Free Lemonade, Little C.H.A.D., Hive Mind, Soul Locket, Black Hole, Aquarius, No. 2, The Sad Onion, Gello, Saturnus, Act of Contrition, Boom!, Censer, Paschal Candle, Eden's Soul, Pentagram, Seraphim, Stem Cells
Magic Fingers, Consolation Prize, Eye of Greed, Infestation 2, Forget Me Now, Spirit of the Night, Almond Milk, Lachryphagy, Number One, Pluto, Black Lotus, Eye Sore, Yuck Heart, Brittle Bones, Mitre, We Need to Go Deeper!, Dark Matter, Hallowed Ground, Sacrificial Dagger, Pyro, The Scooper, Ghost Bombs, Damocles, Odd Mushroom (Large), Cracked Orb, Transcendence, Mom's Key, Breath of Life, Demon Baby, Robo-Baby, Vasculitis, Infamy, Breakfast, PHD, Orphan Socks, Dad's Ring, Keeper's Sack, 3 Dollar Bill, Rune Bag, Kidney Stone, Habit, Rotten Meat, D4, Succubus, 20/20, Mr. Mega, Mom's Bra, Sol, Guppy's Collar, Raw Liver, Guppy's Eye, Azazel's Rage, Options?, Lusty Blood, Lil Chest, Sack Head, Whore of Babylon, Magneto, Rotten Baby, Echo Chamber, Bob's Curse, Rosary, Backstabber, Haemolacria, Blue Cap, Skeleton Key, The Soul, 7 Seals, Scatter Bombs, 4.5 Volt, Spear of Destiny, Crack Jacks, Bucket of Lard, Night Light, Wooden Spoon, Compost, Multidimensional Baby, The Book of Belial, Abyss, Maw of the Void, Cambion Conception, Judas' Shadow, Gemini (Item), IV Bag, Immaculate Heart, Polyphemus, Supper, Pisces, Pay to Play, Ipecac, Void, Midas' Touch, The Stairway, Guillotine, Satanic Bible, Card Reading, Red Candle, 2Spooky, Unicorn Stump, Scapular, Giant Cell, The Body, Dead Cat, Tiny Planet, Charm of the Vampire, The Nail, Pop!, Anti-Gravity, Mom's Wig, Mars, Charged Baby, Book of Secrets, Sworn Protector, Guppy's Hair Ball, Vade Retro, Dark Prince's Crown, Bursting Sack, Mini Mush, Punching Bag, Luna, Monstrance, Coupon, Terra, Brother Bobby, Greed's Gullet, Slipped Rib, Lil Delirium, Akeldama, Abel, D1, Epic Fetus, Marrow, The Compass, Mega Blast, Wait What?, Empty Vessel, Screw, Immaculate Conception, Midnight Snack, Vengeful Spirit, Little Baggy, Lil Haunt, The Ludovico Technique, Super Bandage
Circle of Protection, Mom's Lipstick, Finger!, BBF, The Belt, Lost Soul, Capricorn, Dr. Fetus, Lil Brimstone, Hungry Soul, Lil Abaddon, Purity, Sharp Straw, Stigmata, Bloody Lust, Mom's Box, Sack of Pennies, Sack of Sacks, Bloody Gust, A Quarter, Dessert, Acid Baby, YO LISTEN!, Bomb Bag, Isaac's Heart, False PHD, Sister Maggy, Eraser, Forever Alone, Glass Cannon, Brimstone Bombs, Missing Page 2, Monster Manual, Trinity Shield, Spider Bite, Meat Cleaver, My Reflection, Poke Go, X-Ray Vision, Mr. Boom, Clear Rune, Lazarus' Rags, Betrayal, ???'s Only Friend, Cancer, Marked, Plan C, Guppy's Paw, The Book of Sin, Purgatory, Dad's Lost Coin, Bot Fly, Gimpy, A Pound of Flesh, Celtic Cross, <3, 120 Volt, Samson's Chains, Lord of the Pit, Shade, Guppy's Tail, Piggy Bank, Best Bud, Hypercoagulation, Sanguine Bond, Dark Bum, Jupiter, Continuum, Large Zit, The Negative, God's Flesh, Razor Blade, Heartbreak, Venus, Mom's Pad, Mercurius, Key Bum, Obsessed Fan, Spelunker Hat, Ghost Baby, Black Powder, 1up!, Strawman, Death's List, Delirious, Blood Oath, Ouija Board, The Necronomicon, Strange Attractor, Lil Spewer, D10, Mom's Shovel, Aries
Broken Shovel, Milk!, Headless Baby, Wavy Cap, Eye Drops, The Bean, GB Bug, Wire Coat Hanger, Infestation, Mom's Heels, Mom's Coin Purse, Taurus, TMTRAINER, Big Chubby, Tonsil, Steven (Item)
