A list of all items from The Binding of Isaac: Rebirth, ranked from best to worst. We combined votes from 68 players to create this list. Based on the latest version of The Binding of Isaac: Repentance.
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Glitched Crown, SMB Super Fan, Holy Grail, Sacred Heart, Apple!, Toxic Shock, PJs, Glass Eye, Red Key
Lemegeton, The Sad Onion, Death Certificate, Birthright, Jacob's Ladder, Tooth Picks, Diplopia, Blood of the Martyr, Black Candle, Book of Revelations, Cat-O-Nine-Tails, Technology, Placenta, Eucharist, Steam Sale, Ghost Pepper, Twisted Pair, The D6, C Section, Humbleing Bundle, Wire Coat Hanger, Mom's Knife, Red Stew, Crooked Penny, Little Horn (Item), Sausage, Spindown Dice, Divorce Papers, R Key, Tropicamide, Godhead, Magic Scab, Holy Mantle, Pluto, Lunch, The Parasite, Dead Onion, Synthoil, The Mind, Sharp Plug, Sinus Infection, A Bar of Soap, Champion Belt, D Infinity, Salvation, Holy Light, Technology Zero, Suplex!, Tech X, Spirit Sword, My Reflection, Playdough Cookie, Bird's Eye, Mr. Dolly, Urn of Souls, Options?, Blank Card, Dark Arts, Bot Fly, The Virus, Sacred Orb, Ceremonial Robes, Mysterious Liquid, Magic 8 Ball, Redemption, Greed's Gullet, The Small Rock, Tech.5, Dead Eye, Cambion Conception, Experimental Treatment, Analog Stick, Nancy Bombs, Odd Mushroom (Large), Serpent's Kiss, Sack Head, Abaddon, Magic Fingers, Chocolate Milk, Death's Touch, Little Steven, Lost Contact, Raw Liver, The Ladder, Pop!, Stigmata, Contagion, Dad's Key, Marbles, YO LISTEN!, Card Reading, Gello, The Stairway, Bobby-Bomb, Fortune Cookie, Squeezy, Consolation Prize, Paschal Candle, Orphan Socks, 4.5 Volt, Iron Bar, The Nail, The Soul, The Relic, Spoon Bender, 1up!, Shoop Da Whoop!, Head of the Keeper, Lodestone, 8 Inch Nails, Fruit Cake, Explosivo, Technology 2, Dark Matter, Finger!, Montezuma's Revenge, Psy Fly, Guppy's Eye
Incubus, Brimstone, Crown of Light, Schoolbag, Cricket's Head, Chaos, 3 Dollar Bill, Papa Fly, Capricorn, Binky, Euthanasia, Curse of the Tower, Bozo, Luna, Revelation, Eternal D6, Genesis, Tractor Beam, Smelter, Cain's Other Eye, Mars, Host Hat, Member Card, Rainbow Baby, BFFS!, More Options, Hot Bombs, Safety Pin, Sissy Longlegs, Jar of Wisps, Mom's Perfume, Bloody Gust, Tough Love, Angelic Prism, Damocles, Rubber Cement, Yum Heart, Magic Mushroom, Rock Bottom, Starter Deck, Box of Friends, Mitre, Dad's Ring, Pentagram, The Wafer, Golden Razor, Match Book, Bogo Bombs, Pyromaniac, A Pony, Monstro's Lung, Scorpio, Doctor's Remote, Eye of Belial, The Mark, Bird Cage, Gimpy, My Little Unicorn, Ocular Rift, Rotten Baby, Mega Mush, Loki's Horns, Uranus, Trisagion, Crystal Ball, Stop Watch, Deep Pockets, Leo, Belly Jelly, Missing No., Tarot Cloth, Soul Locket, Eden's Soul, Black Hole, Glitter Bombs, The Compass, Dead Cat, The Pact, Cancer, Guardian Angel, Hallowed Ground, The Ludovico Technique, Odd Mushroom (Thin), The Candle, Lil Gurdy, Sack of Pennies, E. Coli, Saturnus, Almond Milk, Charm of the Vampire, Soy Milk, Deck of Cards, Money = Power, Alabaster Box, Eye Drops, Dry Baby, Act of Contrition, Moving Box, Placebo, D4, Mom's Key, Rosary, Roid Rage, Book of Secrets, Sad Bombs, Prayer Card, The Poop, Crack Jacks, Night Light, Rune Bag, Sticky Bombs, Plum Flute, Robo-Baby 2.0, The Boomerang, X-Ray Vision, The Book of Belial, Evil Charm, Pyro, Seraphim, Screw, The Belt, Cracked Orb, Guppy's Collar, Maw of the Void, Belly Button, Vengeful Spirit, Anti-Gravity, Mom's Wig, Sworn Protector, Sacrificial Dagger, Spear of Destiny, Magneto, Scatter Bombs, Echo Chamber, Flip, Bomb Bag, Polyphemus, Little Baggy, Continuum, Midas' Touch, Lil Chest, Midnight Snack, Lusty Blood, 20/20, Backstabber, Immaculate Conception, Lil Abaddon, Blanket, Eve's Mascara, Haemolacria, The Wiz, Aries, Multidimensional Baby, Mini Mush, Skeleton Key, Mr. Boom, Bloody Lust, Sack of Sacks, Freezer Baby, Jupiter, 7 Seals, Spelunker Hat, Ipecac, Box, Spin to Win, Converter, Speed Ball, Venus, There's Options, Buddy in a Box, Empty Heart, Spirit of the Night, Forget Me Now, Ouija Board, Cursed Eye, Dataminer
Old Bandage, Pageant Boy, Taurus, Dark Bum, Black Powder, Purgatory, Kidney Stone, Guppy's Paw, Mega Blast, Epic Fetus, Lost Soul, Dr. Fetus, Abyss, Dessert, A Snack, Mercurius, Sanguine Bond, Void, A Quarter, Binge Eater, Heartbreak, Satanic Bible, A Lump of Coal, Mutant Spider, Goat Head
Infamy, Censer, Cricket's Body, Blood Bag, Mystery Sack, Eye of the Occult, Harlequin Baby, Vanishing Twin, Bob's Curse, Spider Mod, Mr. Mega, Divine Intervention, Brittle Bones, The Body, Astral Projection, Mom's Shovel, Jaw Bone, Circle of Protection, Cone Head, Duality, Big Fan, My Shadow, Sacrificial Altar, A Dollar, Robo-Baby, Isaac's Tomb, Pointy Rib, Contract From Below, Glaucoma, The Polaroid, Virgo, Mystery Gift, Tooth and Nail, ???'s Only Friend, The Mulligan, The Book of Sin, A Pound of Flesh, Daddy Longlegs, Parasitoid, Demon Baby, Portable Slot, Fast Bombs, Broken Glass Cannon, Best Bud, Sulfur, Guppy's Head, Little Chubby, The Peeper, Bomber Boy, The Swarm, Whore of Babylon, MEAT!, The Battery, Blue Map, Treasure Map, Athame, Book of the Dead, Aquarius, Succubus, Neptunus, Hive Mind, Rotten Meat, PHD, We Need to Go Deeper!, Keeper's Box, Boom!, Lucky Foot, Azazel's Rage, Lachryphagy, 2Spooky, Ball of Bandages, Judas' Shadow, Brother Bobby, Keeper's Sack, Black Lotus, Infestation 2, Fire Mind, False PHD, Ghost Bombs, Transcendence, Immaculate Heart, Blood Clot, Eye Sore, Sol, Bucket of Lard, D7, Metal Plate, Book of Virtues, Wooden Spoon, Scapular, Larynx, Yuck Heart, Habit, Terra, Mom's Ring, Giant Cell, Broken Shovel, Dogma (Item), Spirit Shackles, No. 2, BBF, Empty Vessel, Tiny Planet, Slipped Rib, Breath of Life, Acid Baby, Guppy's Hair Ball, Punching Bag, Abel, Crack the Sky, Brimstone Bombs, Monster Manual, Gemini (Item), Number One, Lil Delirium, Bursting Sack, Inner Child, Mom's Contacts, Mystery Egg, Lord of the Pit, Lil Monstro, Blood Rights, The Scooper, Missing Page 2, Ventricle Razor, Flush!, Free Lemonade, Growth Hormones, Wooden Nickel, Mom's Lipstick, Teleport!, Monstrance, Compound Fracture, Gnawed Leaf, Mom's Eyeshadow, Mom's Bottle of Pills, Lil Brimstone, Supper, Akeldama
Dark Prince's Crown, Jesus Juice, Box of Spiders, Hungry Soul, Samson's Chains, D1, Pisces, Lil Haunt, Breakfast, Lemon Mishap, Eye of Greed, Dull Razor, Mom's Bra, Betrayal, Pay to Play, Maggy's Bow, Plan C, D100, Lazarus' Rags, Bum Friend, Marrow, Everything Jar, Jumper Cables, IV Bag, Butt Bombs, Friend Zone, Forever Alone, Vade Retro, Decap Attack, Mom's Purse, Blue Cap, Vasculitis, Candy Heart, Shade, Guppy's Tail, Kidney Bean, <3, Wait What?, Distant Admiration, Red Candle, Mom's Box, Super Bandage, Purity, Little C.H.A.D., Isaac's Heart, Poke Go, Unicorn Stump, Charged Baby, Dad's Lost Coin, Rotten Tomato, Sister Maggy, Dinner, Fate, Isaac's Tears, Pause, Holy Water, Broken Watch, Razor Blade, Sharp Straw, Skatole, Best Friend, Fate's Reward, Monstro's Tooth, Tear Detonator, Boiled Baby, Trinity Shield, Scissors, Berserk!, Glass Cannon, Esau Jr., 120 Volt, The Negative, The Hourglass, Smart Fly, Polydactyly, Death's List, Clear Rune, D8, Bob's Rotten Head, Celtic Cross, Pandora's Box, Meat Cleaver, Eraser, Stem Cells, Piggy Bank, Mom's Eye, Guillotine, Hypercoagulation, Compost, Marked, It Hurts, God's Flesh, Key Bum, Blood Oath, Large Zit, Ghost Baby, Sprinkler, Varicose Veins, Dead Tooth, Coupon, Bumbo, The Pinking Shears, Mom's Pad, Lil Spewer, Juicy Sack, Obsessed Fan, Spider Bite, The Necronomicon, Mr. ME!, Strawman, Dad's Note, Cube Baby, Shard of Glass, Quints, Headless Baby, Delirious, Remote Detonator, Hushy, Lil Loki, Milk!, IBS, D10, Wavy Cap, Hemoptysis, Strange Attractor, Angry Fly, Mom's Coin Purse, Infestation, Key Piece 2, Mom's Heels, Dead Sea Scrolls, GB Bug, Spider Butt, Keeper's Kin, The Bean, Head of Krampus, Halo of Flies, Bloodshot Eye, Mongo Baby, Jar of Flies, Notched Axe, Mom's Underwear, Mom's Bracelet, Big Chubby, TMTRAINER, Chemical Peel, Hold, Lost Fly, Undefined, Farting Baby, Knockout Drops, Steven (Item), Tonsil, 9 Volt, Anemic, Ankh, Bob's Brain, Depression, Bone Spurs, Mom's Razor, Torn Photo, Zodiac, Brown Nugget, The Black Bean, Stye, Blood Puppy, Butter Bean, Epiphora, Little Gish, Sagittarius, Ball of Tar, Battery Pack