The Hardest Slay the Spire Bosses - Hardest Tier List

A list of all Slay the Spire bosses, ranked from hardest to easiest.

We combined votes from 9 players to create this list. Boss fights

are typically the most challenging fights you'll face in Slay the

Spire. The hardest bosses have ended numerous runs. All bosses pose

a threat, but some are more consistently difficult than others to

overcome.