The Binding of Isaac Items Tier List

S

A

B

C

D

F

S Tier

Death Certificate, Sacred Heart, Glitched Crown

A Tier

C Section, Twisted Pair, R Key, The D6, Sacred Orb, Godhead, Holy Mantle, Mom's Knife, Spindown Dice, Brimstone, D Infinity, Tech X, Incubus, Psy Fly, Cricket's Head, Magic Mushroom, Rock Bottom, Jacob's Ladder, A Lump of Coal, Crown of Light, Goat Head, Trisagion, Mutant Spider, The Parasite, Diplopia, Red Key, Birthright, More Options, The Wafer, Holy Light, Stop Watch, Ghost Pepper, Ceremonial Robes, Pyromaniac, Chaos, Athame, Succubus, Revelation, The Stairway, Technology, 20/20, Dead Eye, Spoon Bender, Apple!, Technology Zero, The Mark, Mystery Gift, Tractor Beam, Mega Mush, Immaculate Heart, Backstabber, Polyphemus, Spirit Sword, Eternal D6, Abaddon, Cricket's Body, Death's Touch, Eye of Belial, Haemolacria, Binge Eater, The Pact, Host Hat, 8 Inch Nails, Blood of the Martyr, Tough Love, Flip, Lusty Blood, Pluto, Bird's Eye, Eucharist, Sausage, Explosivo, Dogma (Item), The Halo, Maw of the Void, Rubber Cement, Book of Revelations, Bag of Crafting, SMB Super Fan, Black Candle, Gnawed Leaf, Cancer, Tech.5, Star of Bethlehem, YO LISTEN!, Squeezy, Fruit Cake, Rotten Baby, The Mind, Dead Dove, Terra, Daddy Longlegs, Guppy's Eye, Capricorn, Growth Hormones, Head of the Keeper, Fire Mind, Pentagram, Dead Cat

B Tier

Monstro's Lung, Genesis, Steam Sale, Mucormycosis, Little Horn (Item), The Small Rock, Dark Matter, Paschal Candle, Ocular Rift, The Battery, Technology 2, The Inner Eye, The Soul, Binky, Lachryphagy, Forget Me Now, Money = Power, Guppy's Tail, Proptosis, Ipecac, Libra, Purity, Damocles, Wire Coat Hanger, Book of Virtues, Lemegeton, My Reflection, Holy Grail, Blue Map, Cat-O-Nine-Tails, Eden's Blessing, Lost Contact, Mom's Contacts, Lord of the Pit, Member Card, Stigmata, Eye of the Occult, Toxic Shock, Angelic Prism, PHD, Seraphim, Stapler, Voodoo Head, Habit, Mr. Dolly, Synthoil, Mama Mega!, Bot Fly, Restock, Eve's Mascara, Car Battery, Uranus, Duality, Humbleing Bundle, Lucky Foot, The Sad Onion, Dog Tooth, Rosary, A Dollar, Red Stew, Sulfur, Infestation 2, Lodestone, Sack Head, Sulfuric Acid, Odd Mushroom (Large), Dark Arts, Infamy, Continuum, Worm Friend, Knockout Drops, Satanic Bible, Lil Brimstone, Euthanasia, Lil Dumpy, Camo Undies, The Intruder, 9 Volt, PJs, Champion Belt, 4.5 Volt, Sagittarius, Book of Shadows, Roid Rage, X-Ray Vision, Soy Milk, Spirit of the Night, 1up!, Black Lotus, Flat Stone, Lil Abaddon, Act of Contrition, Rune Bag, We Need to Go Deeper!, Lead Pencil, Blue Cap, Placenta, Chocolate Milk, Neptunus, Blanket, Tooth Picks, Divorce Papers, Scorpio, Whore of Babylon, A Bar of Soap, Judas' Shadow, Pyro, Mom's Key, Eden's Soul, Saturnus, Mysterious Liquid, There's Options, Gello, Blank Card, Dead Onion, The Body, Salvation, Epic Fetus, Parasitoid, Dark Bum, 7 Seals, Mom's Pearls, Playdough Cookie, Compound Fracture, 3 Dollar Bill, Sinus Infection, Schoolbag, Ouija Board, Scapular, Echo Chamber, Gimpy, Void, Options?, Mitre, Guppy's Paw, Transcendence, Crystal Ball, Monstrance, Mom's Ring, Sharp Plug, Alabaster Box, BFFS!, Censer, The Ludovico Technique, Leech, Contagion, Cupid's Arrow, Treasure Map, Holy Water, Urn of Souls, Torn Photo, Dr. Fetus, Jumper Cables, Charged Baby, Serpent's Kiss, Charm of the Vampire, Keeper's Sack, Freezer Baby, Eye Drops, Coupon, The Mulligan, Fate, Sacrificial Altar, Virgo, The Relic, Brittle Bones, Guppy's Collar, Tarot Cloth, Abyss, Guppy's Head, Trinity Shield, Sacrificial Dagger, Mini Mush, Skeleton Key, Odd Mushroom (Thin), Pisces, Glass Eye, Dad's Ring, Almond Milk, The Book of Belial, False PHD, Tropicamide, Divine Intervention, Mega Blast, Analog Stick, Pop!, Raw Liver, Sol, Marbles, Fanny Pack, A Pony, The Polaroid, Spider Mod, Consolation Prize, D20

C Tier

Luna, Magic Scab, Mr. ME!, Crooked Penny, Dry Baby, Box of Friends, Bozo, Bloody Lust, Broken Modem, Cambion Conception, 120 Volt, Book of the Dead, Steven (Item), MEAT!, Blood Bag, Prayer Card, White Pony, Orphan Socks, Hungry Soul, Cube of Meat, Mom's Eye, Kidney Stone, Spelunker Hat, Pupula Duplex, Glitter Bombs, Magic 8 Ball, The Compass, Quints, Jesus Juice, Starter Deck, Black Hole, Adrenaline, Contract From Below, Aquarius, Old Bandage, Glowing Hourglass, Mars, Suplex!, Book of Secrets, Cain's Other Eye, Redemption, Little Steven, Astral Projection, Buddy in a Box, The Negative, D100, Chemical Peel, Tammy's Head, Speed Ball, Cone Head, Multidimensional Baby, Maggy's Bow, Tooth and Nail, Lil Loki, Mongo Baby, Lil Monstro, Mom's Perfume, Blood Clot, Rotten Tomato, Yum Heart, Death's List, Midas' Touch, Ghost Bombs, Inner Child, Soul Locket, The Bible, Scatter Bombs, Screw, Sissy Longlegs, Clear Rune, Iron Bar, The Nail, Metal Plate, Bloody Gust, The Peeper, Loki's Horns, Dream Catcher, Moving Box, Everything Jar, Belly Button, Card Reading, Dad's Key, Butt Bombs, Mom's Purse, Deep Pockets, Anti-Gravity, Ankh, Gemini (Item), Evil Charm, Pandora's Box, Rainbow Baby, Anemic, The Swarm, Mercurius, Purgatory, Smart Fly, The Common Cold, D1, Big Fan, Caffeine Pill, Fruity Plum, Super Bandage, Evil Eye, Halo of Flies, Telepathy for Dummies, Brother Bobby, Tiny Planet, Spider Bite, Mr. Mega, Montezuma's Revenge, Harlequin Baby, Aries, Acid Baby, Spear of Destiny, Azazel's Rage, Hive Mind, Wooden Nickel, Latch Key, Marrow, Spiderbaby, Robo-Baby, Dad's Lost Coin, Robo-Baby 2.0, Belly Jelly, Demon Baby, The Ladder, Bomber Boy, Lil Portal, Boom!, Boiled Baby, Immaculate Conception, Glyph of Balance, Hallowed Ground, Anima Sola, The Book of Sin, Empty Vessel, Rocket in a Jar, Lunch, Spirit Shackles, Sworn Protector, Magic Skin, Brimstone Bombs, Sack of Pennies, Stem Cells, Sad Bombs, Circle of Protection, Bogo Bombs, Fate's Reward, Smelter, Dark Prince's Crown, Shoop Da Whoop!, Mystery Sack, Papa Fly, King Baby, Stye, Distant Admiration, Taurus, Plum Flute, Sticky Bombs, Finger!, Greed's Gullet, Epiphora, Skatole, Lil Chest, Juicy Sack, Ghost Baby, Guardian Angel, Guppy's Hair Ball, Little C.H.A.D., Vengeful Spirit, Zodiac, Stitches, Lost Soul, Number One, BBF, Cube Baby, Black Powder, Breakfast, Lil Gurdy, Large Zit, No. 2, Isaac's Tomb, Deck of Cards, ???'s Only Friend, Dead Bird, Polydactyly, Bursting Sack, Blood Bombs, Vade Retro, Lazarus' Rags, Eye of Greed, A Quarter, Vanishing Twin, Cracked Orb, The Candle, Jupiter, Sack of Sacks, Monster Manual, Key Piece 1, Box of Spiders, Celtic Cross, Safety Pin, Abel, Recall, Telekinesis, Wooden Spoon, The Virus, Venus, Berserk!, Decap Attack, Pageant Boy, Bum Friend, Hot Bombs, Hypercoagulation, Teleport 2.0, Ball of Bandages, Mom's Eyeshadow, Piggy Bank, Headless Baby, Box, Bone Spurs, Lost Fly, The Belt, Varicose Veins, Giant Cell

D Tier

Larynx, Midnight Snack, Vasculitis, Lil Delirium, Bloodshot Eye, Lil Haunt, Betrayal, A Snack, Bobby-Bomb, Booster Pack (Item), Isaac's Tears, Fast Bombs, Bob's Brain, Match Book, Isaac's Heart, Red Candle, Placebo, 2Spooky, Sister Maggy, Bob's Curse, My Little Unicorn, Eye Sore, Jar of Wisps, Esau Jr., D4, Crack the Sky, Fortune Cookie, IV Bag, God's Flesh, Thunder Thighs, Crack Jacks, Notched Axe, D8, Friend Zone, How to Jump, Dull Razor, Leo, It Hurts, Dead Tooth, Potato Peeler, Sanguine Bond, Experimental Treatment, Mom's Lipstick, My Shadow, Head of Krampus, Magic Fingers, Best Bud, Guillotine, The Necronomicon, Ball of Tar, D7, Little Chubby, Mom's Box, Glass Cannon, The Hourglass, Hushy, Mom's Coin Purse, Dinner, Breath of Life, Bucket of Lard, Obsessed Fan, Eraser, Little Gish, Rotten Meat, Heartbreak, Broken Watch, Mom's Wig, Wavy Cap, Milk!, Bomb Bag, Friend Finder, <3, Sumptorium, Night Light, Jaw Bone, Tinytoma, Sprinkler, Dirty Mind, Depression, Nancy Bombs, Sharp Straw, Ventricle Razor, Mystery Egg, Keeper's Box, Mom's Bottle of Pills, Scissors, Strange Attractor, Akeldama, Friendly Ball, Mom's Razor, Unicorn Stump, Bird Cage, Key Bum, Lemon Mishap, Supper, A Pound of Flesh, Slipped Rib, Linger Bean, The Pinking Shears, Battery Pack, The Gamekid, Angry Fly, Hemoptysis, Delirious, Candy Heart, Farting Baby, Key Piece 2, Portable Slot, The Boomerang, Strawman, Plan C, IBS, Poke Go, Mr. Boom, Converter, Glaucoma, Pointy Rib, GB Bug, Samson's Chains, Undefined, Pay to Play, Infestation, Cursed Eye, Missing Page 2, Empty Heart, Blood Oath, Free Lemonade, Forever Alone, Shade, Flush!, Spider Butt, E. Coli, Mine Crafter, The Jar, Dessert, Metronome, Lil Spewer, Teleport!, Punching Bag, Big Chubby, Magneto, Little Baggy, Marked, Leprosy, The Scooper, Wait What?, Mom's Underwear, Mom's Bracelet, Doctor's Remote, Best Friend, Dad's Note, Yuck Heart, Mom's Shovel, Remote Detonator, The Poop, Missing No., Mega Bean, Mom's Heels, Meat Cleaver, Dead Sea Scrolls, Shard of Glass, Razor Blade, The Wiz, Clicker, Mom's Bra, Hold, Knife Piece 2, Blood Puppy, TMTRAINER, Tonsil, Anarchist Cookbook, Blood Rights, Keeper's Kin, Monstro's Tooth, Bumbo, Compost, Jar of Flies, Brown Nugget, Sharp Key, Bob's Rotten Head, Curse of the Tower, Kamikaze!, The Bean, Tear Detonator, Dataminer, Spin to Win, D10, Butter Bean, Broken Shovel, D12, Pause, Knife Piece 1, Broken Glass Cannon, Golden Razor, Kidney Bean

F Tier

The Black Bean, Mom's Pad