The Binding of Isaac Items Tier List

S

A

B

C

D

F

S Tier

Death Certificate, Sacred Heart, Glitched Crown

A Tier

C Section, Twisted Pair, Godhead, Sacred Orb, R Key, The D6, Holy Mantle, Mom's Knife, Spindown Dice, D Infinity, Tech X, Brimstone, Cricket's Head, Psy Fly, Incubus, Magic Mushroom, Mutant Spider, Jacob's Ladder, Crown of Light, Trisagion, Goat Head, A Lump of Coal, More Options, Stop Watch, Red Key, The Parasite, The Wafer, Rock Bottom, Pyromaniac, Apple!, Ceremonial Robes, Diplopia, Holy Light, Revelation, Athame, Eternal D6, Technology Zero, Birthright, Succubus, 20/20, Mega Mush, Cricket's Body, Chaos, The Stairway, Spoon Bender, Ghost Pepper, Pluto, Polyphemus, Binge Eater, Dead Eye, Flip, 8 Inch Nails, Host Hat, Gnawed Leaf, The Mind, Fire Mind, Immaculate Heart, The Mark, Technology, Little Horn (Item), Haemolacria, Dark Matter, Backstabber, Binky, Steam Sale, The Pact, Money = Power, Rubber Cement, Blood of the Martyr, Eye of Belial, Death's Touch, Abaddon, Mystery Gift, Duality, Head of the Keeper, Eden's Blessing, Tractor Beam, Tough Love, Black Candle, The Battery, Soy Milk, Bag of Crafting, Bird's Eye, Sausage, The Small Rock, Explosivo, Mucormycosis, Spirit Sword, Growth Hormones

B Tier

Ocular Rift, Guppy's Tail, Tech.5, Stigmata, Cat-O-Nine-Tails, SMB Super Fan, Holy Grail, The Halo, Book of Revelations, Cancer, Pentagram, Capricorn, Lusty Blood, Technology 2, Blue Map, Monstro's Lung, Dead Cat, Genesis, Tooth Picks, Eucharist, Wire Coat Hanger, Libra, Squeezy, Dead Dove, Knockout Drops, Placenta, Forget Me Now, Daddy Longlegs, PJs, Lemegeton, Rotten Baby, Maw of the Void, Guppy's Eye, Lachryphagy, Damocles, Fruit Cake, Mom's Contacts, Lodestone, Almond Milk, Rosary, YO LISTEN!, Dogma (Item), Proptosis, Paschal Candle, Blanket, Blank Card, Red Stew, Lost Contact, Sacrificial Altar, Champion Belt, Sharp Plug, The Soul, Ipecac, Terra, Book of Virtues, Car Battery, Spider Mod, Eve's Mascara, Tarot Cloth, Star of Bethlehem, Voodoo Head, 4.5 Volt, Sulfur, Purity, Dark Arts, Fate, Lord of the Pit, Uranus, Humbleing Bundle, Mom's Pearls, Saturnus, My Reflection, Stapler, Book of Shadows, Member Card, Lead Pencil, Sagittarius, Sulfuric Acid, Mama Mega!, Angelic Prism, A Dollar, Gimpy, 1up!, Monstrance, The Inner Eye, The Sad Onion, Synthoil, Toxic Shock, Eye of the Occult, Playdough Cookie, Satanic Bible, Dog Tooth, Sinus Infection, Continuum, Coupon, The Ludovico Technique, Flat Stone, Whore of Babylon, Sacrificial Dagger, Habit, Mom's Key, Blue Cap, Scapular, Euthanasia, Restock, Infamy, Pisces, Guppy's Paw, Roid Rage, Act of Contrition, Contagion, 9 Volt, Spirit of the Night, Void, Mr. Dolly, The Intruder, Pyro, Odd Mushroom (Large), 7 Seals, Treasure Map, Tropicamide, X-Ray Vision, Eden's Soul, Leech, Bot Fly, We Need to Go Deeper!, Infestation 2, Salvation, Lucky Foot, Torn Photo, Gello, Neptunus, Worm Friend, Transcendence, Guppy's Collar, Seraphim, Keeper's Sack, Serpent's Kiss, There's Options, Lil Dumpy, Charm of the Vampire, Chocolate Milk, White Pony, Ouija Board, Sack Head, Dead Onion, Jumper Cables, Rune Bag, A Bar of Soap, Mysterious Liquid, Trinity Shield, Glass Eye, Alabaster Box, Abyss, Crystal Ball, Eye Drops, Freezer Baby, Echo Chamber, The Body, Compound Fracture, BFFS!, Mitre, Dark Bum, PHD, Epic Fetus, Black Lotus, Pupula Duplex, Dr. Fetus, Charged Baby, Guppy's Head, Scorpio, Options?, Pop!, Schoolbag, Fanny Pack, Censer, Blood Bag, Dad's Ring, Cambion Conception, Marbles, Urn of Souls, Camo Undies, 3 Dollar Bill, Astral Projection, Kidney Stone, Magic 8 Ball, Skeleton Key, Speed Ball, Rotten Tomato, The Mulligan, Scatter Bombs, Bloody Lust

C Tier

Metal Plate, Odd Mushroom (Thin), Mr. ME!, Jesus Juice, Mega Blast, Analog Stick, Mom's Purse, Magic Scab, False PHD, Judas' Shadow, Mom's Perfume, Cupid's Arrow, Lil Brimstone, Mini Mush, The Polaroid, Adrenaline, Consolation Prize, Tiny Planet, Crooked Penny, Cube of Meat, Cone Head, Yum Heart, Glitter Bombs, Parasitoid, The Compass, Azazel's Rage, Orphan Socks, The Bible, Papa Fly, Multidimensional Baby, Book of Secrets, The Relic, Lil Abaddon, Divorce Papers, D20, The Nail, Sticky Bombs, Holy Water, Divine Intervention, The Book of Belial, Mom's Ring, Smelter, Midas' Touch, Sissy Longlegs, Big Fan, MEAT!, Screw, Hungry Soul, Aquarius, Dry Baby, Contract From Below, Hallowed Ground, Ghost Bombs, Mom's Eye, Spider Bite, Luna, Lunch, Virgo, Starter Deck, Little Steven, Magic Skin, 120 Volt, Box of Friends, Book of the Dead, Safety Pin, Deep Pockets, Mars, Evil Charm, Bozo, Vanishing Twin, Maggy's Bow, Broken Modem, Soul Locket, Marrow, Greed's Gullet, Chemical Peel, Spelunker Hat, Suplex!, Moving Box, Gemini (Item), Dad's Lost Coin, Anemic, Isaac's Tomb, Taurus, Montezuma's Revenge, A Pony, Brother Bobby, Brittle Bones, Old Bandage, Guppy's Hair Ball, Raw Liver, Loki's Horns, Boom!, Eye of Greed, Skatole, Belly Button, Lil Portal, Quints, Iron Bar, Number One, Card Reading, Caffeine Pill, Black Hole, Redemption, Breakfast, Varicose Veins, Telepathy for Dummies, Tooth and Nail, Smart Fly, Empty Vessel, Purgatory, Dad's Key, Rainbow Baby, Evil Eye, Anima Sola, Mercurius, Spear of Destiny, The Ladder, Ankh, Cain's Other Eye, Buddy in a Box, Prayer Card, The Common Cold, Halo of Flies, Immaculate Conception, Bogo Bombs, Acid Baby, No. 2, Dark Prince's Crown, Rocket in a Jar, Shoop Da Whoop!, Inner Child, Dream Catcher, Sol, Zodiac, Glyph of Balance, Stye, Latch Key, Robo-Baby, Monster Manual, Plum Flute, Giant Cell, Butt Bombs, Box of Spiders, Cracked Orb, The Negative, The Candle, Blood Bombs, Blood Clot, The Swarm, The Book of Sin, D1, Sack of Pennies, Epiphora, Distant Admiration, Everything Jar, Lil Monstro, Lil Loki, Lost Soul, Glowing Hourglass, Boiled Baby, Clear Rune, Spiderbaby, Bomber Boy, Experimental Treatment, Thunder Thighs, Spirit Shackles, Hive Mind, Sumptorium, Bloody Gust, Black Powder, Harlequin Baby, The Virus, Robo-Baby 2.0, Steven (Item), Sworn Protector, Mystery Sack, Mongo Baby, Stem Cells, Sad Bombs, Tammy's Head, Venus, ???'s Only Friend, Little C.H.A.D., BBF, Glaucoma, Recall, Death's List, D100, Sister Maggy, Vade Retro, Box, Berserk!, Bobby-Bomb, Pandora's Box, Dead Bird, Placebo, The Peeper, Stitches, Larynx, Bob's Curse, Large Zit, Vengeful Spirit, A Quarter, Fast Bombs, The Belt, Bloodshot Eye, Fate's Reward, Mom's Eyeshadow, Brimstone Bombs, Obsessed Fan, Cube Baby, Key Piece 1, Juicy Sack, My Shadow, Betrayal, Celtic Cross, Bone Spurs

D Tier

Super Bandage, Lil Chest, Bum Friend, Mr. Mega, Belly Jelly, Jar of Wisps, A Pound of Flesh, Pageant Boy, Jaw Bone, D4, Ghost Baby, Fortune Cookie, Glass Cannon, Polydactyly, Head of Krampus, Mom's Lipstick, King Baby, Lil Haunt, Aries, Wooden Nickel, Circle of Protection, Ball of Tar, Finger!, Vasculitis, 2Spooky, Lil Gurdy, Bursting Sack, Mom's Box, Night Light, Midnight Snack, How to Jump, Ventricle Razor, Hot Bombs, Lil Delirium, Keeper's Box, Isaac's Tears, Pay to Play, My Little Unicorn, Lemon Mishap, Wooden Spoon, Decap Attack, The Hourglass, Mystery Egg, Lost Fly, Deck of Cards, Telekinesis, Cursed Eye, Sack of Sacks, Friendly Ball, Crack Jacks, Crack the Sky, Mom's Razor, Friend Zone, Demon Baby, Key Bum, Potato Peeler, Abel, Little Baggy, Bob's Brain, Pointy Rib, Hypercoagulation, Fruity Plum, Strange Attractor, Match Book, Metronome, Mom's Wig, Teleport 2.0, Lazarus' Rags, Leo, Magic Fingers, Dead Tooth, E. Coli, Sanguine Bond, Piggy Bank, Ball of Bandages, Converter, Broken Watch, Mom's Underwear, Supper, Guardian Angel, Eye Sore, Best Bud, Hushy, Missing No., Candy Heart, Tinytoma, Empty Heart, Infestation, Linger Bean, Jupiter, Dad's Note, IV Bag, Undefined, Free Lemonade, Guillotine, Booster Pack (Item), Wavy Cap, Rotten Meat, Razor Blade, D7, Shade, Mom's Bracelet, God's Flesh, Mom's Bottle of Pills, Dinner, Little Gish, Sharp Straw, Bucket of Lard, Bomb Bag, Dessert, Strawman, IBS, Headless Baby, D8, Esau Jr., Dull Razor, Plan C, Bird Cage, Missing Page 2, Samson's Chains, Sprinkler, Scissors, The Poop, Flush!, Mom's Coin Purse, The Pinking Shears, Mr. Boom, Hemoptysis, Blood Oath, TMTRAINER, Key Piece 2, Teleport!, Anti-Gravity, Isaac's Heart, Punching Bag, Dirty Mind, Portable Slot, The Boomerang, Milk!, Akeldama, The Necronomicon, Yuck Heart, Battery Pack, Red Candle, Unicorn Stump, Blood Rights, Nancy Bombs, Breath of Life, Clicker, Notched Axe, Depression, Delirious, It Hurts, Angry Fly, Heartbreak, Poke Go, Eraser, Mom's Bra, <3, A Snack, Dead Sea Scrolls, Doctor's Remote, Magneto, Friend Finder, Spider Butt, Slipped Rib, GB Bug, Lil Spewer, Forever Alone, Tonsil, The Gamekid, Hold, Best Friend, Meat Cleaver, The Bean, Mom's Heels, The Wiz, Leprosy, Remote Detonator, Compost, Tear Detonator, Brown Nugget, Mega Bean, Wait What?, Little Chubby, Kamikaze!, Mine Crafter, Dataminer, Spin to Win, Marked, Knife Piece 2, Blood Puppy, Anarchist Cookbook, Bob's Rotten Head, Monstro's Tooth, The Scooper, D12, The Jar, Farting Baby, Shard of Glass, Broken Glass Cannon, D10, Big Chubby, Golden Razor, Kidney Bean, Sharp Key, Curse of the Tower, Mom's Shovel, Jar of Flies, Pause, Knife Piece 1, Keeper's Kin, The Black Bean, Bumbo, Butter Bean, Broken Shovel

F Tier

Mom's Pad