A list of all secret room items from The Binding of Isaac: Rebirth, ranked from best to worst.
We combined votes from 120 players to create this list.
Based on the latest version of The Binding of Isaac: Repentance.
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Death Certificate, Glitched Crown
Sacred Orb, R Key, Spindown Dice, D Infinity, Red Key, Rock Bottom, Eternal D6, Chaos
Sausage, Mega Mush, Flip, Lost Contact, Binge Eater, Forget Me Now, 1up!, Blank Card, Pyro, We Need to Go Deeper!, Odd Mushroom (Large), Echo Chamber, Infamy, Sack Head, Keeper's Sack, Transcendence, Rune Bag, Black Lotus
Skeleton Key, Epic Fetus, Orphan Socks, Astral Projection, Dad's Ring, Odd Mushroom (Thin), Inner Child, Book of Secrets, Raw Liver, Evil Charm, Isaac's Tomb, Mystery Sack, Eye of Greed, Clear Rune, Vanishing Twin, Greed's Gullet
Cracked Orb, Sack of Pennies, Spirit Shackles, A Quarter, Mr. Mega, Lost Soul, Sack of Sacks, Placebo, Esau Jr., Key Bum, Keeper's Box, Bomb Bag, The Necronomicon, Wavy Cap, Cursed Eye, Missing No., Missing Page 2, Samson's Chains, Strawman, GB Bug, TMTRAINER
Compost, Keeper's Kin
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