A list of all secret room items from The Binding of Isaac: Rebirth, ranked from best to worst.
We combined votes from 113 players to create this list.
Based on the latest version of The Binding of Isaac: Repentance.
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Death Certificate, Glitched Crown
Sacred Orb, R Key, Spindown Dice, D Infinity, Red Key, Rock Bottom, Eternal D6, Chaos
Sausage, Lost Contact, Mega Mush, Flip, Binge Eater, 1up!, Blank Card, Forget Me Now, Infamy, We Need to Go Deeper!, Echo Chamber, Sack Head, Odd Mushroom (Large), Pyro, Keeper's Sack, Transcendence, Rune Bag, Astral Projection
Skeleton Key, Black Lotus, Dad's Ring, Orphan Socks, Odd Mushroom (Thin), Epic Fetus, Isaac's Tomb, Book of Secrets, Vanishing Twin, Evil Charm, Eye of Greed, Raw Liver, Greed's Gullet, Mystery Sack, Inner Child, Cracked Orb, Clear Rune, Lost Soul
A Quarter, Sack of Pennies, Spirit Shackles, Placebo, Keeper's Box, Mr. Mega, Cursed Eye, Sack of Sacks, Key Bum, Wavy Cap, Missing No., Esau Jr., Strawman, Bomb Bag, TMTRAINER, Missing Page 2, Samson's Chains, The Necronomicon, Compost, GB Bug
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