A list of all secret room items from The Binding of Isaac: Rebirth, ranked from best to worst.
We combined votes from 110 players to create this list.
Based on the latest version of The Binding of Isaac: Repentance.
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Death Certificate, Glitched Crown
Sacred Orb, R Key, Spindown Dice, D Infinity, Red Key, Rock Bottom, Eternal D6, Chaos
Sausage, Lost Contact, Flip, Mega Mush, Binge Eater, 1up!, Forget Me Now, Blank Card, Infamy, We Need to Go Deeper!, Echo Chamber, Pyro, Sack Head, Odd Mushroom (Large), Keeper's Sack, Skeleton Key, Rune Bag, Astral Projection, Transcendence, Dad's Ring, Black Lotus
Epic Fetus, Book of Secrets, Evil Charm, Orphan Socks, Odd Mushroom (Thin), Greed's Gullet, Isaac's Tomb, Vanishing Twin, Mystery Sack, Eye of Greed, Raw Liver, Inner Child, Cracked Orb, Sack of Pennies, Lost Soul, Spirit Shackles, Clear Rune
A Quarter, Mr. Mega, Keeper's Box, Sack of Sacks, Key Bum, Placebo, Missing No., Esau Jr., Cursed Eye, Wavy Cap, Strawman, TMTRAINER, Bomb Bag, Samson's Chains, Missing Page 2, The Necronomicon, Compost, GB Bug
Keeper's Kin
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