The Best Activated Items
A list of all activated items from The Binding of Isaac: Rebirth, ranked from best to worst.
We combined votes from 78 players to create this list.
Based on the latest version of The Binding of Isaac: Repentance.
Vote Now171 Items
1.7K Votes
78 Voters
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Rating
1.Death Certificate
60100Rating0.3
Spread2.Red Key
2.Red Key
Quality 3Ultra Secret RoomSecret RoomActivatedKey MasterCurse RoomRed Chest6100Rating0.9
Spread6100Rating0.9
Spread3.Mama Mega!
399Rating2.5
Spread4.Bag of Crafting
496Rating2.4
Spread5.Book of Shadows
495Rating2.4
Spread6.Diplopia
692Rating4
Spread7.Eternal D6
692Rating1.7
Spread8.Book of Virtues
891Rating3.1
Spread9.Crooked Penny
691Rating3.1
Spread10.D20
489Rating8.3
Spread11.The D6
5988Rating0.3
Spread12.R Key
6087Rating0.4
Spread13.Mystery Gift
486Rating5.7
Spread14.Spindown Dice
6186Rating0.4
Spread15.White Pony
485Rating9.4
Spread16.Shoop Da Whoop!
684Rating5
Spread17.Lemegeton
784Rating4.5
Spread18.Yum Heart
583Rating4.8
Spread19.D Infinity
6078Rating0.6
Spread20.Book of Revelations
778Rating5
Spread21.Blank Card
576Rating3.4
Spread22.Box of Friends
576Rating6.3
Spread23.Genesis
776Rating3.7
Spread24.Mr. ME!
475Rating8.4
Spread25.Wooden Nickel
475Rating9.7
Spread26.Mega Bean
475Rating9.7
Spread27.Eden's Soul
974Rating3.4
Spread28.Sulfur
972Rating3.6
Spread29.Black Hole
672Rating6.1
Spread30.Dark Arts
872Rating3.7
Spread31.Magic Skin
471Rating10
Spread32.The Bible
470Rating9.9
Spread33.Sumptorium
370Rating9.4
Spread34.Teleport 2.0
367Rating10.4
Spread35.The Candle
566Rating7
Spread36.Smelter
566Rating11
Spread37.Gello
765Rating4.6
Spread38.Keeper's Box
665Rating5.1
Spread39.Suplex!
664Rating7.3
Spread40.Prayer Card
663Rating6.7
Spread41.Crack the Sky
563Rating11.5
Spread42.Deck of Cards
562Rating7.7
Spread43.Moving Box
461Rating8.2
Spread44.A Pony
560Rating6.9
Spread45.Ventricle Razor
560Rating11
Spread46.Damocles
960Rating4.1
Spread47.Alabaster Box
559Rating7.2
Spread48.Golden Razor
459Rating9
Spread49.We Need to Go Deeper!
1057Rating3.6
Spread50.Mega Mush
6357Rating0.4
Spread51.Forget Me Now
1157Rating3.1
Spread52.Head of Krampus
556Rating10.1
Spread53.Larynx
556Rating4.9
Spread54.Everything Jar
555Rating10.3
Spread55.Sacrificial Altar
654Rating8.2
Spread56.Coupon
653Rating7.1
Spread57.Potato Peeler
453Rating15
Spread58.Urn of Souls
652Rating8.5
Spread59.D7
552Rating4.7
Spread60.Crystal Ball
652Rating6.6
Spread61.Flip
5751Rating0.5
Spread62.Dad's Key
451Rating14
Spread63.Box of Spiders
451Rating6.7
Spread64.My Little Unicorn
650Rating6.4
Spread65.The Book of Belial
1150Rating3.2
Spread66.Sharp Straw
650Rating7.3
Spread67.Glowing Hourglass
449Rating13.8
Spread68.IV Bag
649Rating7.4
Spread69.Jar of Wisps
649Rating7.4
Spread70.D1
749Rating4.9
Spread71.The Nail
1048Rating5.1
Spread72.Magic Fingers
648Rating7.8
Spread73.Plum Flute
647Rating8.4
Spread74.Book of the Dead
747Rating6.1
Spread75.Lemon Mishap
446Rating5.6
Spread76.Isaac's Tears
546Rating10
Spread77.Guppy's Paw
1046Rating4.5
Spread78.Book of Secrets
646Rating5.4
Spread79.How to Jump
544Rating10.6
Spread80.Guppy's Head
743Rating4
Spread81.Dataminer
743Rating6.1
Spread82.Teleport!
543Rating8.1
Spread83.Blood Rights
643Rating8.2
Spread84.Doctor's Remote
541Rating7.9
Spread85.Monstro's Tooth
541Rating10.2
Spread86.Void
5840Rating0.4
Spread87.Satanic Bible
5640Rating0.5
Spread88.Pandora's Box
539Rating7.8
Spread89.Friend Finder
338Rating17.8
Spread90.Decap Attack
638Rating8.3
Spread91.Plan C
91.Plan C
Ultra Secret RoomQuality 0ActivatedDevil BeggarCurse RoomRed ChestShopDevil Room1038Rating4.5
Spread1038Rating4.5
Spread92.Notched Axe
437Rating7.6
Spread93.The Book of Sin
1036Rating3.8
Spread94.Stitches
436Rating12.5
Spread94.Anima Sola
436Rating12.5
Spread96.Scissors
535Rating7.4
Spread97.Eraser
735Rating6.8
Spread98.Best Friend
635Rating8.1
Spread99.Telekinesis
635Rating9.3
Spread100.Abyss
6034Rating0.5
Spread101.The Jar
334Rating7.1
Spread102.D4
634Rating5.3
Spread103.Clear Rune
632Rating7.1
Spread104.Sharp Key
431Rating5.7
Spread105.Mega Blast
5431Rating0.5
Spread106.The Scooper
630Rating8.2
Spread107.Mom's Bra
730Rating6.8
Spread108.Berserk!
630Rating6.7
Spread109.Mom's Box
629Rating4.2
Spread110.Portable Slot
829Rating5.3
Spread111.Mr. Boom
729Rating4
Spread112.Razor Blade
829Rating5.6
Spread113.The Boomerang
528Rating7.2
Spread114.D12
428Rating9.7
Spread115.Free Lemonade
528Rating9.8
Spread116.Recall
328Rating17.3
Spread117.Tammy's Head
427Rating8.9
Spread118.Yuck Heart
726Rating5.2
Spread119.Spin to Win
426Rating8.4
Spread120.Broken Glass Cannon
725Rating6.9
Spread121.Wavy Cap
625Rating8
Spread122.Dull Razor
724Rating4.5
Spread123.Undefined
624Rating6.3
Spread124.Mom's Bottle of Pills
124.Mom's Bottle of Pills
Quality 1Treasure RoomOld ChestBeggarActivatedDevil BeggarCrane GameShop624Rating6.9
Spread624Rating6.9
Spread125.The Poop
524Rating6.5
Spread126.Flush!
724Rating7.1
Spread127.Monster Manual
923Rating2.9
Spread128.Placebo
622Rating5.3
Spread129.D100
522Rating5.9
Spread130.The Hourglass
621Rating7.2
Spread131.Breath of Life
720Rating3.9
Spread132.D8
620Rating4.2
Spread133.Remote Detonator
133.Remote Detonator
Quality 1Ultra Secret RoomTreasure RoomBomb BumActivatedCrane GameShop620Rating5
Spread620Rating5
Spread134.Fortune Cookie
519Rating7
Spread135.Vade Retro
719Rating4.4
Spread136.Glass Cannon
619Rating3.1
Spread137.Bob's Rotten Head
619Rating5.3
Spread138.Metronome
419Rating6.5
Spread138.Friendly Ball
419Rating6.5
Spread140.Converter
419Rating6.5
Spread141.Dead Sea Scrolls
518Rating5
Spread142.Meat Cleaver
617Rating4.3
Spread143.Unicorn Stump
717Rating3.5
Spread144.Mom's Pad
916Rating2
Spread145.Wait What?
816Rating4.3
Spread146.Esau Jr.
515Rating5.5
Spread147.Telepathy for Dummies
415Rating11.1
Spread148.Spider Butt
515Rating4.4
Spread149.Tear Detonator
514Rating5.3
Spread150.Pause
514Rating4.8
Spread151.Red Candle
614Rating4.8
Spread152.Kidney Bean
713Rating4
Spread153.D10
612Rating3.3
Spread154.The Pinking Shears
510Rating2.5
Spread155.Hold
610Rating5.6
Spread156.Clicker
49Rating8.2
Spread157.The Gamekid
49Rating7.6
Spread157.Anarchist Cookbook
49Rating7.6
Spread159.Sprinkler
77Rating2.2
Spread160.The Necronomicon
107Rating1.7
Spread161.Compost
76Rating2
Spread162.Broken Shovel
616Rating0.3
Spread163.Brown Nugget
56Rating5.4
Spread164.Delirious
85Rating2.3
Spread165.Mom's Shovel
555Rating0.3
Spread166.Jar of Flies
54Rating1.5
Spread167.Mom's Bracelet
51Rating0.6
Spread168.The Bean
50Rating0.3
Spread169.Kamikaze!
40Rating0.4
Spread170.Butter Bean
40Rating0.4
Spread171.Mine Crafter
50Rating0.3
Spread
