The Best Secret Room Items Ranked List

67 Items

1.7K Votes

110 Voters

52%Consensus

Updated 2/18/26

A list of all secret room items from The Binding of Isaac: Rebirth, ranked from best to worst.

We combined votes from 110 players to create this list.

Based on the latest version of The Binding of Isaac: Repentance.

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1.Death Certificate
1.Death Certificate
Secret Room
Quality 4
Activated
86
100
Rating
84
CONS
86
100
Rating
84
CONS

2.Glitched Crown
2.Glitched Crown
Passive
Secret Room
Quality 4
88
98
Rating
72
CONS
88
98
Rating
72
CONS

3.Sacred Orb
3.Sacred Orb
Angel Room
Passive
Secret Room
Quality 4
89
89
Rating
57
CONS
89
89
Rating
57
CONS

4.R Key
4.R Key
Secret Room
Quality 4
Activated
87
88
Rating
56
CONS
87
88
Rating
56
CONS

5.Spindown Dice
5.Spindown Dice
Treasure Room
Secret Room
Quality 4
Activated
Crane Game
87
87
Rating
55
CONS
87
87
Rating
55
CONS

6.D Infinity
6.D Infinity
Treasure Room
Secret Room
Quality 4
Activated
87
83
Rating
51
CONS
87
83
Rating
51
CONS

7.Red Key
7.Red Key
Quality 3
Ultra Secret Room
Secret Room
Activated
Key Master
Curse Room
Red Chest
14
79
Rating
61
CONS
14
79
Rating
61
CONS

8.Rock Bottom
8.Rock Bottom
Quality 3
Passive
Secret Room
15
77
Rating
56
CONS
15
77
Rating
56
CONS

9.Eternal D6
9.Eternal D6
Quality 3
Treasure Room
Secret Room
Activated
Crane Game
14
75
Rating
58
CONS
14
75
Rating
58
CONS

10.Chaos
10.Chaos
Quality 3
Passive
Secret Room
Shop
17
72
Rating
55
CONS
17
72
Rating
55
CONS

11.Sausage
11.Sausage
Quality 3
Passive
Secret Room
16
64
Rating
43
CONS
16
64
Rating
43
CONS

12.Lost Contact
12.Lost Contact
Quality 2
Passive
Treasure Room
Secret Room
14
58
Rating
36
CONS
14
58
Rating
36
CONS

13.Flip
13.Flip
Ultra Secret Room
Secret Room
Quality 4
Activated
Curse Room
85
56
Rating
56
CONS
85
56
Rating
56
CONS

14.Mega Mush
14.Mega Mush
Treasure Room
Secret Room
Quality 4
Activated
90
56
Rating
57
CONS
90
56
Rating
57
CONS

15.Binge Eater
15.Binge Eater
Passive
Secret Room
Quality 4
86
56
Rating
60
CONS
86
56
Rating
60
CONS

16.1up!
16.1up!
Quality 2
Passive
Secret Room
14
55
Rating
41
CONS
14
55
Rating
41
CONS

17.Forget Me Now
17.Forget Me Now
Quality 3
Treasure Room
Secret Room
Activated
Devil Beggar
Devil Room
18
52
Rating
50
CONS
18
52
Rating
50
CONS

18.Blank Card
18.Blank Card
Quality 2
Treasure Room
Secret Room
Activated
Shop
12
51
Rating
40
CONS
12
51
Rating
40
CONS

19.Infamy
19.Infamy
Quality 2
Passive
Treasure Room
Secret Room
Golden Chest
16
51
Rating
45
CONS
16
51
Rating
45
CONS

20.We Need to Go Deeper!
20.We Need to Go Deeper!
Quality 2
Secret Room
Activated
Devil Room
18
49
Rating
43
CONS
18
49
Rating
43
CONS

21.Echo Chamber
21.Echo Chamber
Quality 3
Passive
Ultra Secret Room
Secret Room
15
49
Rating
32
CONS
15
49
Rating
32
CONS

22.Pyro
22.Pyro
Quality 3
Passive
Treasure Room
Secret Room
Bomb Bum
15
45
Rating
42
CONS
15
45
Rating
42
CONS

23.Sack Head
23.Sack Head
Quality 3
Passive
Secret Room
Shop
16
45
Rating
32
CONS
16
45
Rating
32
CONS

24.Odd Mushroom (Large)
24.Odd Mushroom (Large)
Quality 2
Passive
Treasure Room
Secret Room
15
44
Rating
34
CONS
15
44
Rating
34
CONS

25.Keeper's Sack
25.Keeper's Sack
Quality 3
Passive
Secret Room
Shop
15
44
Rating
35
CONS
15
44
Rating
35
CONS

26.Skeleton Key
26.Skeleton Key
Quality 3
Passive
Treasure Room
Secret Room
15
43
Rating
39
CONS
15
43
Rating
39
CONS

27.Rune Bag
27.Rune Bag
Quality 3
Passive
Treasure Room
Secret Room
Golden Chest
13
43
Rating
41
CONS
13
43
Rating
41
CONS

28.Astral Projection
28.Astral Projection
Quality 2
Passive
Treasure Room
Secret Room
12
42
Rating
32
CONS
12
42
Rating
32
CONS

29.Transcendence
29.Transcendence
Quality 3
Passive
Secret Room
15
42
Rating
36
CONS
15
42
Rating
36
CONS

30.Dad's Ring
30.Dad's Ring
Quality 3
Passive
Old Chest
Secret Room
14
42
Rating
38
CONS
14
42
Rating
38
CONS

31.Black Lotus
31.Black Lotus
Quality 2
Passive
Secret Room
13
41
Rating
41
CONS
13
41
Rating
41
CONS

32.Epic Fetus
32.Epic Fetus
Passive
Treasure Room
Secret Room
Quality 4
86
36
Rating
68
CONS
86
36
Rating
68
CONS

33.Book of Secrets
33.Book of Secrets
Quality 1
Treasure Room
Secret Room
Activated
Library
13
36
Rating
33
CONS
13
36
Rating
33
CONS

34.Evil Charm
34.Evil Charm
Quality 2
Passive
Secret Room
11
35
Rating
33
CONS
11
35
Rating
33
CONS

35.Orphan Socks
35.Orphan Socks
Quality 2
Passive
Secret Room
Golden Chest
16
35
Rating
35
CONS
16
35
Rating
35
CONS

36.Odd Mushroom (Thin)
36.Odd Mushroom (Thin)
Quality 2
Passive
Treasure Room
Secret Room
17
34
Rating
35
CONS
17
34
Rating
35
CONS

37.Greed's Gullet
37.Greed's Gullet
Passive
Quality 1
Secret Room
14
34
Rating
36
CONS
14
34
Rating
36
CONS

38.Isaac's Tomb
38.Isaac's Tomb
Quality 3
Passive
Secret Room
13
33
Rating
25
CONS
13
33
Rating
25
CONS

39.Vanishing Twin
39.Vanishing Twin
Quality 2
Passive
Secret Room
Curse Room
12
32
Rating
30
CONS
12
32
Rating
30
CONS

40.Mystery Sack
40.Mystery Sack
Quality 2
Passive
Treasure Room
Beggar
Secret Room
Golden Chest
18
32
Rating
33
CONS
18
32
Rating
33
CONS

41.Eye of Greed
41.Eye of Greed
Quality 2
Passive
Secret Room
14
31
Rating
33
CONS
14
31
Rating
33
CONS

42.Raw Liver
42.Raw Liver
Quality 2
Passive
Secret Room
13
31
Rating
38
CONS
13
31
Rating
38
CONS

43.Inner Child
43.Inner Child
Quality 2
Passive
Secret Room
13
30
Rating
35
CONS
13
30
Rating
35
CONS

44.Cracked Orb
44.Cracked Orb
Passive
Quality 1
Treasure Room
Secret Room
15
29
Rating
35
CONS
15
29
Rating
35
CONS

45.Sack of Pennies
45.Sack of Pennies
Passive
Quality 1
Treasure Room
Secret Room
Golden Chest
14
27
Rating
35
CONS
14
27
Rating
35
CONS

46.Lost Soul
46.Lost Soul
Quality 2
Passive
Baby Shop
Treasure Room
Secret Room
13
26
Rating
35
CONS
13
26
Rating
35
CONS

47.Spirit Shackles
47.Spirit Shackles
Quality 2
Passive
Secret Room
14
25
Rating
36
CONS
14
25
Rating
36
CONS

48.Clear Rune
48.Clear Rune
Quality 2
Secret Room
Activated
Crane Game
12
24
Rating
40
CONS
12
24
Rating
40
CONS

49.A Quarter
49.A Quarter
Passive
Treasure Room
Quality 0
Secret Room
Devil Room
Golden Chest
22
22
Rating
49
CONS
22
22
Rating
49
CONS

50.Mr. Mega
50.Mr. Mega
Quality 2
Passive
Treasure Room
Secret Room
Bomb Bum
13
22
Rating
42
CONS
13
22
Rating
42
CONS

51.Keeper's Box
51.Keeper's Box
Quality 2
Secret Room
Activated
Wooden Chest
Shop
12
22
Rating
52
CONS
12
22
Rating
52
CONS

52.Sack of Sacks
52.Sack of Sacks
Quality 3
Passive
Secret Room
Shop
Golden Chest
16
19
Rating
46
CONS
16
19
Rating
46
CONS

53.Key Bum
53.Key Bum
Passive
Baby Shop
Treasure Room
Quality 0
Secret Room
Key Master
14
19
Rating
37
CONS
14
19
Rating
37
CONS

54.Placebo
54.Placebo
Quality 2
Secret Room
Activated
Shop
14
18
Rating
42
CONS
14
18
Rating
42
CONS

55.Missing No.
55.Missing No.
Passive
Quality 0
Secret Room
10
17
Rating
38
CONS
10
17
Rating
38
CONS

56.Esau Jr.
56.Esau Jr.
Quality 2
Ultra Secret Room
Treasure Room
Secret Room
Activated
11
16
Rating
39
CONS
11
16
Rating
39
CONS

57.Cursed Eye
57.Cursed Eye
Passive
Treasure Room
Quality 0
Secret Room
Red Chest
13
15
Rating
39
CONS
13
15
Rating
39
CONS

58.Wavy Cap
58.Wavy Cap
Quality 1
Secret Room
Activated
13
14
Rating
42
CONS
13
14
Rating
42
CONS

59.Strawman
59.Strawman
Quality 2
Passive
Secret Room
14
14
Rating
42
CONS
14
14
Rating
42
CONS

60.TMTRAINER
60.TMTRAINER
Passive
Quality 0
Secret Room
12
13
Rating
43
CONS
12
13
Rating
43
CONS

61.Bomb Bag
61.Bomb Bag
Quality 2
Passive
Treasure Room
Secret Room
Bomb Bum
Golden Chest
15
12
Rating
49
CONS
15
12
Rating
49
CONS

62.Samson's Chains
62.Samson's Chains
Passive
Quality 1
Treasure Room
Secret Room
18
12
Rating
48
CONS
18
12
Rating
48
CONS

63.Missing Page 2
63.Missing Page 2
Passive
Quality 0
Secret Room
Devil Beggar
Devil Room
20
12
Rating
46
CONS
20
12
Rating
46
CONS

64.The Necronomicon
64.The Necronomicon
Quality 1
Secret Room
Activated
Library
Devil Room
19
11
Rating
50
CONS
19
11
Rating
50
CONS

65.Compost
65.Compost
Quality 1
Secret Room
Activated
Shop
Rotten Beggar
12
9
Rating
48
CONS
12
9
Rating
48
CONS

66.GB Bug
66.GB Bug
Passive
Quality 1
Treasure Room
Secret Room
12
8
Rating
49
CONS
12
8
Rating
49
CONS

67.Keeper's Kin
67.Keeper's Kin
Quality 2
Passive
Treasure Room
Secret Room
11
0
Rating
59
CONS
11
0
Rating
59
CONS