The Best Activated Items Tier List

S

A

B

C

D

F

S Tier

Death Certificate

A Tier

R Key, The D6, Spindown Dice, D Infinity, Red Key, Diplopia, Eternal D6, Mega Mush, Mystery Gift, Bag of Crafting, Flip, Book of Virtues, Forget Me Now, Book of Revelations, Lemegeton, Mama Mega!, Genesis, Book of Shadows, Damocles

B Tier

Dark Arts, Satanic Bible, We Need to Go Deeper!, Sulfur, Guppy's Paw, Coupon, Crystal Ball, Void, Eden's Soul, Blank Card, Sacrificial Altar, Gello, Abyss, Yum Heart, Guppy's Head, Mr. ME!, White Pony, Urn of Souls, Mega Blast, A Pony, Stitches, The Book of Belial, D20, Black Hole, Alabaster Box, Book of the Dead, Book of Secrets, Prayer Card, The Nail, Crooked Penny, The Bible, Anima Sola, Box of Friends, Pandora's Box

C Tier

Clear Rune, Telepathy for Dummies, Dad's Key, Glowing Hourglass, Suplex!, D1, Shoop Da Whoop!, Everything Jar, D100, Smelter, The Candle, Moving Box, Tammy's Head, Deck of Cards, Magic Skin, Telekinesis, Recall, Wooden Nickel, Monster Manual, Larynx, D4, The Book of Sin, Box of Spiders, Placebo, Plum Flute, Head of Krampus, My Little Unicorn, Vade Retro, Magic Fingers, Fortune Cookie, Sumptorium, Berserk!, Potato Peeler, Crack the Sky, IV Bag, Mom's Box, Teleport 2.0, How to Jump, Ventricle Razor, Notched Axe, Decap Attack, Friendly Ball, The Necronomicon, The Gamekid, Red Candle, Jar of Wisps, Converter, Dull Razor, Glass Cannon

D Tier

Isaac's Tears, Esau Jr., Mom's Bottle of Pills, Sharp Straw, Eraser, The Hourglass, Unicorn Stump, Scissors, Friend Finder, Mr. Boom, Undefined, Wavy Cap, Breath of Life, Portable Slot, The Boomerang, D8, Delirious, Mine Crafter, Flush!, Teleport!, Keeper's Box, D7, Sprinkler, Plan C, Doctor's Remote, Lemon Mishap, Metronome, Mom's Bracelet, Spider Butt, The Pinking Shears, Yuck Heart, Dead Sea Scrolls, Wait What?, Razor Blade, Mom's Bra, Remote Detonator, Hold, The Poop, Clicker, Free Lemonade, Blood Rights, Best Friend, Bob's Rotten Head, Brown Nugget, Meat Cleaver, Mega Bean, The Jar, Tear Detonator, Mom's Shovel, Dataminer, D10, Kamikaze!, Anarchist Cookbook, Pause, Sharp Key, Monstro's Tooth, Jar of Flies, Spin to Win, The Bean, Broken Shovel, D12, Golden Razor, Broken Glass Cannon, Kidney Bean, The Scooper, Compost

F Tier

Butter Bean, Mom's Pad