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Tuff Twins
The Binding of Isaac: Rebirth
Enemy
4 Total Votes
Tags
Chapter 2.5
Boss
Type
Boss
Location
Chapter 2.5
Rankings
17th
/ 102
The Hardest Binding of Isaac Bosses
3
74
Rating
Tier
12.7
Spread
3
74
Rating
Tier
12.7
Spread
1st
/ 8
The Hardest Chapter 2.5 Bosses
2
100
Rating
S
Tier
15.5
Spread
2
100
Rating
S
Tier
15.5
Spread
