A list of all secret room items from The Binding of Isaac: Rebirth, ranked from best to worst. We combined votes from 51 players to create this list. Based on the latest version of The Binding of Isaac: Repentance.
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Death Certificate, Glitched Crown
Red Key, Eternal D6, Chaos, Blank Card, Spindown Dice, Sausage
Sacred Orb, R Key, D Infinity, Keeper's Box, Mystery Sack, Mr. Mega, Spirit Shackles, Odd Mushroom (Large), Rune Bag, Infamy, Odd Mushroom (Thin), Orphan Socks, Bomb Bag
Cracked Orb, Forget Me Now, Transcendence, Pyro, We Need to Go Deeper!, Dad's Ring, Skeleton Key, Inner Child, Eye of Greed, Lost Soul, Greed's Gullet, Isaac's Tomb, Binge Eater, Flip, Echo Chamber, Mega Mush
Samson's Chains, Clear Rune, Raw Liver, Keeper's Sack, Book of Secrets, Sack of Sacks, Sack of Pennies, Black Lotus, A Quarter, Epic Fetus, 1up!, Missing Page 2
Key Bum, Sack Head, Wavy Cap, Strawman, The Necronomicon, TMTRAINER, GB Bug
