The Best Secret Room Items
A list of all secret room items from The Binding of Isaac: Rebirth, ranked from best to worst. We combined votes from 64 players to create this list. Based on the latest version of The Binding of Isaac: Repentance.
Vote Now66 Items
744 Votes
64 Voters
My Votes
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Rating
1.Glitched Crown
48100Rating0.2
Spread2.Death Certificate
4998Rating0.3
Spread3.Red Key
3.Red Key
Quality 3Ultra Secret RoomSecret RoomActivatedKey MasterCurse RoomRed Chest498Rating1.2
Spread498Rating1.2
Spread4.Chaos
691Rating2.4
Spread5.Sausage
588Rating3.8
Spread6.Eternal D6
487Rating4.4
Spread7.Rock Bottom
383Rating4.4
Spread8.Sacred Orb
5178Rating0.4
Spread9.R Key
4975Rating0.5
Spread10.Blank Card
374Rating6
Spread11.Spindown Dice
5071Rating0.5
Spread12.Echo Chamber
571Rating7.8
Spread13.Rune Bag
368Rating7.1
Spread14.D Infinity
4965Rating0.6
Spread15.Odd Mushroom (Large)
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564Rating5.6
Spread16.Pyro
660Rating4.2
Spread17.Infamy
658Rating4.4
Spread18.We Need to Go Deeper!
658Rating4.6
Spread19.Mr. Mega
458Rating7
Spread20.Dad's Ring
558Rating7.8
Spread21.Transcendence
555Rating5.7
Spread22.Orphan Socks
650Rating5.5
Spread23.Greed's Gullet
549Rating9.1
Spread24.1up!
449Rating13.7
Spread25.Sack of Pennies
548Rating7.4
Spread26.Lost Contact
348Rating15.2
Spread27.Keeper's Box
447Rating6.7
Spread28.Mystery Sack
746Rating4.4
Spread29.Raw Liver
346Rating8.2
Spread30.Forget Me Now
645Rating3.9
Spread31.Bomb Bag
545Rating7
Spread32.Vanishing Twin
344Rating17.1
Spread33.Binge Eater
4842Rating0.7
Spread34.Black Lotus
441Rating6.8
Spread35.Mega Mush
5141Rating0.7
Spread36.Clear Rune
440Rating8.8
Spread37.Skeleton Key
539Rating3.5
Spread38.Flip
4637Rating0.8
Spread39.Astral Projection
337Rating15.2
Spread40.Odd Mushroom (Thin)
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533Rating5.3
Spread41.Spirit Shackles
433Rating7.4
Spread42.Keeper's Sack
533Rating5.5
Spread43.Cursed Eye
332Rating5.5
Spread44.Cracked Orb
531Rating4.7
Spread45.Epic Fetus
4730Rating0.8
Spread46.Sack Head
530Rating8.2
Spread47.Sack of Sacks
629Rating3.1
Spread48.Lost Soul
426Rating4.5
Spread49.Book of Secrets
325Rating0.9
Spread50.Wavy Cap
524Rating9.2
Spread51.Strawman
523Rating9.2
Spread52.Samson's Chains
723Rating3.1
Spread53.Placebo
322Rating6.7
Spread54.Eye of Greed
521Rating4.4
Spread55.Evil Charm
220Rating14.8
Spread56.Inner Child
417Rating6.5
Spread57.A Quarter
917Rating1.7
Spread58.Isaac's Tomb
516Rating7.6
Spread59.Esau Jr.
315Rating8.7
Spread60.Compost
413Rating6
Spread61.Missing Page 2
74Rating1.9
Spread62.Key Bum
42Rating1.4
Spread63.Keeper's Kin
22Rating2.6
Spread64.The Necronomicon
71Rating0.5
Spread65.TMTRAINER
41Rating1
Spread66.GB Bug
30Rating2.5
Spread
