The Best Secret Room Items

A list of all secret room items from The Binding of Isaac: Rebirth, ranked from best to worst. We combined votes from 50 players to create this list. Based on the latest version of The Binding of Isaac: Repentance.

56 Items

505 Votes

50 Voters

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1.Death Certificate
1.Death Certificate
Secret Room
Quality 4
Activated
37
100
Rating
0
Spread
37
100
Rating
0
Spread

2.Glitched Crown
2.Glitched Crown
Passive
Secret Room
Quality 4
36
100
Rating
0
Spread
36
100
Rating
0
Spread

3.Red Key
3.Red Key
Quality 3
Ultra Secret Room
Secret Room
Activated
Key Master
Curse Room
Red Chest
2
95
Rating
3.9
Spread
2
95
Rating
3.9
Spread

4.Eternal D6
4.Eternal D6
Quality 3
Treasure Room
Secret Room
Activated
Crane Game
2
89
Rating
12
Spread
2
89
Rating
12
Spread

5.Chaos
5.Chaos
Quality 3
Passive
Secret Room
Shop
4
80
Rating
3.9
Spread
4
80
Rating
3.9
Spread

6.Blank Card
6.Blank Card
Quality 2
Treasure Room
Secret Room
Activated
Shop
2
78
Rating
13
Spread
2
78
Rating
13
Spread

7.Spindown Dice
7.Spindown Dice
Treasure Room
Secret Room
Quality 4
Activated
Crane Game
37
75
Rating
0.3
Spread
37
75
Rating
0.3
Spread

8.Sausage
8.Sausage
Quality 3
Passive
Secret Room
3
74
Rating
6.9
Spread
3
74
Rating
6.9
Spread

9.Sacred Orb
9.Sacred Orb
Angel Room
Passive
Secret Room
Quality 4
39
73
Rating
0.4
Spread
39
73
Rating
0.4
Spread

10.R Key
10.R Key
Secret Room
Quality 4
Activated
38
71
Rating
0.4
Spread
38
71
Rating
0.4
Spread

11.D Infinity
11.D Infinity
Treasure Room
Secret Room
Quality 4
Activated
38
70
Rating
0.6
Spread
38
70
Rating
0.6
Spread

12.Keeper's Box
12.Keeper's Box
Quality 2
Secret Room
Activated
Wooden Chest
Shop
3
66
Rating
15.8
Spread
3
66
Rating
15.8
Spread

13.Mystery Sack
13.Mystery Sack
Quality 2
Passive
Treasure Room
Beggar
Secret Room
Golden Chest
4
62
Rating
5.4
Spread
4
62
Rating
5.4
Spread

14.Mr. Mega
14.Mr. Mega
Quality 2
Passive
Treasure Room
Secret Room
Bomb Bum
2
60
Rating
14.9
Spread
2
60
Rating
14.9
Spread

15.Spirit Shackles
15.Spirit Shackles
Quality 2
Passive
Secret Room
2
60
Rating
0.4
Spread
2
60
Rating
0.4
Spread

16.Odd Mushroom (Large)
16.Odd Mushroom (Large)
Quality 2
Passive
Treasure Room
Secret Room
3
60
Rating
11.8
Spread
3
60
Rating
11.8
Spread

17.Rune Bag
17.Rune Bag
Quality 3
Passive
Treasure Room
Secret Room
Golden Chest
2
60
Rating
15.2
Spread
2
60
Rating
15.2
Spread

18.Infamy
18.Infamy
Quality 2
Passive
Treasure Room
Secret Room
Golden Chest
4
59
Rating
6.4
Spread
4
59
Rating
6.4
Spread

19.Odd Mushroom (Thin)
19.Odd Mushroom (Thin)
Quality 2
Passive
Treasure Room
Secret Room
3
53
Rating
4.6
Spread
3
53
Rating
4.6
Spread

20.Orphan Socks
20.Orphan Socks
Quality 2
Passive
Secret Room
Golden Chest
4
52
Rating
5.9
Spread
4
52
Rating
5.9
Spread

21.Bomb Bag
21.Bomb Bag
Quality 2
Passive
Treasure Room
Secret Room
Bomb Bum
Golden Chest
3
52
Rating
11.9
Spread
3
52
Rating
11.9
Spread

22.Cracked Orb
22.Cracked Orb
Passive
Quality 1
Treasure Room
Secret Room
3
49
Rating
3.4
Spread
3
49
Rating
3.4
Spread

23.Forget Me Now
23.Forget Me Now
Quality 3
Treasure Room
Secret Room
Activated
Devil Beggar
Devil Room
4
46
Rating
5.5
Spread
4
46
Rating
5.5
Spread

24.Transcendence
24.Transcendence
Quality 3
Passive
Secret Room
3
44
Rating
5
Spread
3
44
Rating
5
Spread

25.Pyro
25.Pyro
Quality 3
Passive
Treasure Room
Secret Room
Bomb Bum
4
44
Rating
3.6
Spread
4
44
Rating
3.6
Spread

26.We Need to Go Deeper!
26.We Need to Go Deeper!
Quality 2
Secret Room
Activated
Devil Room
3
43
Rating
6.1
Spread
3
43
Rating
6.1
Spread

27.Dad's Ring
27.Dad's Ring
Quality 3
Passive
Old Chest
Secret Room
3
40
Rating
4.9
Spread
3
40
Rating
4.9
Spread

28.Skeleton Key
28.Skeleton Key
Quality 3
Passive
Treasure Room
Secret Room
3
39
Rating
7.5
Spread
3
39
Rating
7.5
Spread

29.Inner Child
29.Inner Child
Quality 2
Passive
Secret Room
2
38
Rating
9.6
Spread
2
38
Rating
9.6
Spread

30.Eye of Greed
30.Eye of Greed
Quality 2
Passive
Secret Room
2
36
Rating
12.8
Spread
2
36
Rating
12.8
Spread

31.Lost Soul
31.Lost Soul
Quality 2
Passive
Baby Shop
Treasure Room
Secret Room
2
35
Rating
10.2
Spread
2
35
Rating
10.2
Spread

32.Binge Eater
32.Binge Eater
Passive
Secret Room
Quality 4
36
33
Rating
0.9
Spread
36
33
Rating
0.9
Spread

33.Greed's Gullet
33.Greed's Gullet
Passive
Quality 1
Secret Room
3
33
Rating
6.9
Spread
3
33
Rating
6.9
Spread

34.Isaac's Tomb
34.Isaac's Tomb
Quality 3
Passive
Secret Room
3
32
Rating
16.8
Spread
3
32
Rating
16.8
Spread

35.Flip
35.Flip
Ultra Secret Room
Secret Room
Quality 4
Activated
Curse Room
35
32
Rating
0.9
Spread
35
32
Rating
0.9
Spread

36.Echo Chamber
36.Echo Chamber
Quality 3
Passive
Ultra Secret Room
Secret Room
2
31
Rating
4.7
Spread
2
31
Rating
4.7
Spread

37.Mega Mush
37.Mega Mush
Treasure Room
Secret Room
Quality 4
Activated
39
31
Rating
0.8
Spread
39
31
Rating
0.8
Spread

38.Samson's Chains
38.Samson's Chains
Passive
Quality 1
Treasure Room
Secret Room
5
29
Rating
4.9
Spread
5
29
Rating
4.9
Spread

39.Clear Rune
39.Clear Rune
Quality 2
Secret Room
Activated
Crane Game
2
29
Rating
8
Spread
2
29
Rating
8
Spread

40.Raw Liver
40.Raw Liver
Quality 2
Passive
Secret Room
2
29
Rating
11.8
Spread
2
29
Rating
11.8
Spread

41.Keeper's Sack
41.Keeper's Sack
Quality 3
Passive
Secret Room
Shop
3
26
Rating
4.4
Spread
3
26
Rating
4.4
Spread

42.Book of Secrets
42.Book of Secrets
Quality 1
Treasure Room
Secret Room
Activated
Library
2
25
Rating
1.1
Spread
2
25
Rating
1.1
Spread

43.Sack of Sacks
43.Sack of Sacks
Quality 3
Passive
Secret Room
Shop
Golden Chest
4
25
Rating
4.8
Spread
4
25
Rating
4.8
Spread

44.Sack of Pennies
44.Sack of Pennies
Passive
Quality 1
Treasure Room
Secret Room
Golden Chest
2
23
Rating
5.2
Spread
2
23
Rating
5.2
Spread

45.Black Lotus
45.Black Lotus
Quality 2
Passive
Secret Room
3
22
Rating
7.4
Spread
3
22
Rating
7.4
Spread

46.A Quarter
46.A Quarter
Passive
Treasure Room
Quality 0
Secret Room
Devil Room
Golden Chest
7
17
Rating
2.4
Spread
7
17
Rating
2.4
Spread

47.Epic Fetus
47.Epic Fetus
Passive
Treasure Room
Secret Room
Quality 4
35
17
Rating
0.8
Spread
35
17
Rating
0.8
Spread

48.1up!
48.1up!
Quality 2
Passive
Secret Room
2
10
Rating
4.8
Spread
2
10
Rating
4.8
Spread

49.Missing Page 2
49.Missing Page 2
Passive
Quality 0
Secret Room
Devil Beggar
Devil Room
5
8
Rating
3.4
Spread
5
8
Rating
3.4
Spread

50.Key Bum
50.Key Bum
Passive
Baby Shop
Treasure Room
Quality 0
Secret Room
Key Master
2
5
Rating
1.6
Spread
2
5
Rating
1.6
Spread

51.Sack Head
51.Sack Head
Quality 3
Passive
Secret Room
Shop
2
5
Rating
13.6
Spread
2
5
Rating
13.6
Spread

52.Wavy Cap
52.Wavy Cap
Quality 1
Secret Room
Activated
3
5
Rating
2.5
Spread
3
5
Rating
2.5
Spread

53.Strawman
53.Strawman
Quality 2
Passive
Secret Room
3
3
Rating
0.9
Spread
3
3
Rating
0.9
Spread

54.The Necronomicon
54.The Necronomicon
Quality 1
Secret Room
Activated
Library
Devil Room
4
3
Rating
0.7
Spread
4
3
Rating
0.7
Spread

55.TMTRAINER
55.TMTRAINER
Passive
Quality 0
Secret Room
2
2
Rating
2.4
Spread
2
2
Rating
2.4
Spread

56.GB Bug
56.GB Bug
Passive
Quality 1
Treasure Room
Secret Room
2
0
Rating
5.7
Spread
2
0
Rating
5.7
Spread