The Best Secret Room Items

A list of all secret room items from The Binding of Isaac: Rebirth, ranked from best to worst. We combined votes from 60 players to create this list. Based on the latest version of The Binding of Isaac: Repentance.

66 Items

673 Votes

60 Voters

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1.Glitched Crown
1.Glitched Crown
Passive
Secret Room
Quality 4
44
100
Rating
0.1
Spread
44
100
Rating
0.1
Spread

2.Death Certificate
2.Death Certificate
Secret Room
Quality 4
Activated
45
95
Rating
0.4
Spread
45
95
Rating
0.4
Spread

3.Red Key
3.Red Key
Quality 3
Ultra Secret Room
Secret Room
Activated
Key Master
Curse Room
Red Chest
4
94
Rating
1.6
Spread
4
94
Rating
1.6
Spread

4.Sausage
4.Sausage
Quality 3
Passive
Secret Room
4
83
Rating
4.9
Spread
4
83
Rating
4.9
Spread

5.Blank Card
5.Blank Card
Quality 2
Treasure Room
Secret Room
Activated
Shop
3
80
Rating
5.4
Spread
3
80
Rating
5.4
Spread

6.Spindown Dice
6.Spindown Dice
Treasure Room
Secret Room
Quality 4
Activated
Crane Game
46
75
Rating
0.4
Spread
46
75
Rating
0.4
Spread

7.Eternal D6
7.Eternal D6
Quality 3
Treasure Room
Secret Room
Activated
Crane Game
3
74
Rating
8.3
Spread
3
74
Rating
8.3
Spread

8.Odd Mushroom (Large)
8.Odd Mushroom (Large)
Quality 2
Passive
Treasure Room
Secret Room
5
74
Rating
5.4
Spread
5
74
Rating
5.4
Spread

9.R Key
9.R Key
Secret Room
Quality 4
Activated
45
73
Rating
0.5
Spread
45
73
Rating
0.5
Spread

10.Sacred Orb
10.Sacred Orb
Angel Room
Passive
Secret Room
Quality 4
47
73
Rating
0.4
Spread
47
73
Rating
0.4
Spread

11.Chaos
11.Chaos
Quality 3
Passive
Secret Room
Shop
5
72
Rating
3.5
Spread
5
72
Rating
3.5
Spread

12.D Infinity
12.D Infinity
Treasure Room
Secret Room
Quality 4
Activated
45
71
Rating
0.6
Spread
45
71
Rating
0.6
Spread

13.Rock Bottom
13.Rock Bottom
Quality 3
Passive
Secret Room
2
68
Rating
7.9
Spread
2
68
Rating
7.9
Spread

14.Orphan Socks
14.Orphan Socks
Quality 2
Passive
Secret Room
Golden Chest
5
67
Rating
5.3
Spread
5
67
Rating
5.3
Spread

15.1up!
15.1up!
Quality 2
Passive
Secret Room
3
66
Rating
15.9
Spread
3
66
Rating
15.9
Spread

16.Greed's Gullet
16.Greed's Gullet
Passive
Quality 1
Secret Room
4
60
Rating
8.8
Spread
4
60
Rating
8.8
Spread

17.Rune Bag
17.Rune Bag
Quality 3
Passive
Treasure Room
Secret Room
Golden Chest
3
60
Rating
6.6
Spread
3
60
Rating
6.6
Spread

18.Odd Mushroom (Thin)
18.Odd Mushroom (Thin)
Quality 2
Passive
Treasure Room
Secret Room
4
56
Rating
2.5
Spread
4
56
Rating
2.5
Spread

19.Bomb Bag
19.Bomb Bag
Quality 2
Passive
Treasure Room
Secret Room
Bomb Bum
Golden Chest
4
55
Rating
6.3
Spread
4
55
Rating
6.3
Spread

20.Dad's Ring
20.Dad's Ring
Quality 3
Passive
Old Chest
Secret Room
5
54
Rating
7
Spread
5
54
Rating
7
Spread

21.Raw Liver
21.Raw Liver
Quality 2
Passive
Secret Room
3
54
Rating
11.4
Spread
3
54
Rating
11.4
Spread

22.Cracked Orb
22.Cracked Orb
Passive
Quality 1
Treasure Room
Secret Room
4
53
Rating
2.1
Spread
4
53
Rating
2.1
Spread

23.Pyro
23.Pyro
Quality 3
Passive
Treasure Room
Secret Room
Bomb Bum
5
50
Rating
2.5
Spread
5
50
Rating
2.5
Spread

24.Forget Me Now
24.Forget Me Now
Quality 3
Treasure Room
Secret Room
Activated
Devil Beggar
Devil Room
6
46
Rating
4
Spread
6
46
Rating
4
Spread

25.Sack Head
25.Sack Head
Quality 3
Passive
Secret Room
Shop
4
46
Rating
12.6
Spread
4
46
Rating
12.6
Spread

26.Skeleton Key
26.Skeleton Key
Quality 3
Passive
Treasure Room
Secret Room
5
46
Rating
4.1
Spread
5
46
Rating
4.1
Spread

27.Sack of Pennies
27.Sack of Pennies
Passive
Quality 1
Treasure Room
Secret Room
Golden Chest
4
45
Rating
9.3
Spread
4
45
Rating
9.3
Spread

28.Infamy
28.Infamy
Quality 2
Passive
Treasure Room
Secret Room
Golden Chest
6
44
Rating
7
Spread
6
44
Rating
7
Spread

29.Lost Contact
29.Lost Contact
Quality 2
Passive
Treasure Room
Secret Room
2
44
Rating
26.4
Spread
2
44
Rating
26.4
Spread

30.Vanishing Twin
30.Vanishing Twin
Quality 2
Passive
Secret Room
Curse Room
3
44
Rating
16.9
Spread
3
44
Rating
16.9
Spread

31.Echo Chamber
31.Echo Chamber
Quality 3
Passive
Ultra Secret Room
Secret Room
4
43
Rating
4.5
Spread
4
43
Rating
4.5
Spread

32.Book of Secrets
32.Book of Secrets
Quality 1
Treasure Room
Secret Room
Activated
Library
3
42
Rating
6.2
Spread
3
42
Rating
6.2
Spread

33.Sack of Sacks
33.Sack of Sacks
Quality 3
Passive
Secret Room
Shop
Golden Chest
6
42
Rating
5.7
Spread
6
42
Rating
5.7
Spread

34.Mystery Sack
34.Mystery Sack
Quality 2
Passive
Treasure Room
Beggar
Secret Room
Golden Chest
6
41
Rating
6.5
Spread
6
41
Rating
6.5
Spread

35.Lost Soul
35.Lost Soul
Quality 2
Passive
Baby Shop
Treasure Room
Secret Room
4
40
Rating
6.1
Spread
4
40
Rating
6.1
Spread

36.Mega Mush
36.Mega Mush
Treasure Room
Secret Room
Quality 4
Activated
48
40
Rating
0.7
Spread
48
40
Rating
0.7
Spread

37.Mr. Mega
37.Mr. Mega
Quality 2
Passive
Treasure Room
Secret Room
Bomb Bum
4
40
Rating
11.6
Spread
4
40
Rating
11.6
Spread

38.Cursed Eye
38.Cursed Eye
Passive
Treasure Room
Quality 0
Secret Room
Red Chest
3
40
Rating
8
Spread
3
40
Rating
8
Spread

39.Placebo
39.Placebo
Quality 2
Secret Room
Activated
Shop
2
38
Rating
13.8
Spread
2
38
Rating
13.8
Spread

40.Astral Projection
40.Astral Projection
Quality 2
Passive
Treasure Room
Secret Room
3
36
Rating
15.1
Spread
3
36
Rating
15.1
Spread

41.Flip
41.Flip
Ultra Secret Room
Secret Room
Quality 4
Activated
Curse Room
42
35
Rating
0.7
Spread
42
35
Rating
0.7
Spread

42.Spirit Shackles
42.Spirit Shackles
Quality 2
Passive
Secret Room
3
31
Rating
12.9
Spread
3
31
Rating
12.9
Spread

43.A Quarter
43.A Quarter
Passive
Treasure Room
Quality 0
Secret Room
Devil Room
Golden Chest
8
31
Rating
3
Spread
8
31
Rating
3
Spread

44.Epic Fetus
44.Epic Fetus
Passive
Treasure Room
Secret Room
Quality 4
44
30
Rating
0.9
Spread
44
30
Rating
0.9
Spread

45.Binge Eater
45.Binge Eater
Passive
Secret Room
Quality 4
44
30
Rating
0.7
Spread
44
30
Rating
0.7
Spread

46.Evil Charm
46.Evil Charm
Quality 2
Passive
Secret Room
2
29
Rating
20.9
Spread
2
29
Rating
20.9
Spread

47.Transcendence
47.Transcendence
Quality 3
Passive
Secret Room
4
25
Rating
7.2
Spread
4
25
Rating
7.2
Spread

48.We Need to Go Deeper!
48.We Need to Go Deeper!
Quality 2
Secret Room
Activated
Devil Room
5
25
Rating
5.7
Spread
5
25
Rating
5.7
Spread

49.Isaac's Tomb
49.Isaac's Tomb
Quality 3
Passive
Secret Room
4
20
Rating
10.5
Spread
4
20
Rating
10.5
Spread

50.Esau Jr.
50.Esau Jr.
Quality 2
Ultra Secret Room
Treasure Room
Secret Room
Activated
2
20
Rating
15.4
Spread
2
20
Rating
15.4
Spread

51.Samson's Chains
51.Samson's Chains
Passive
Quality 1
Treasure Room
Secret Room
6
19
Rating
4.2
Spread
6
19
Rating
4.2
Spread

52.Inner Child
52.Inner Child
Quality 2
Passive
Secret Room
4
17
Rating
6.5
Spread
4
17
Rating
6.5
Spread

53.Compost
53.Compost
Quality 1
Secret Room
Activated
Shop
Rotten Beggar
3
17
Rating
8.8
Spread
3
17
Rating
8.8
Spread

54.Keeper's Box
54.Keeper's Box
Quality 2
Secret Room
Activated
Wooden Chest
Shop
4
16
Rating
10.5
Spread
4
16
Rating
10.5
Spread

55.Eye of Greed
55.Eye of Greed
Quality 2
Passive
Secret Room
4
16
Rating
6.6
Spread
4
16
Rating
6.6
Spread

56.Keeper's Sack
56.Keeper's Sack
Quality 3
Passive
Secret Room
Shop
4
15
Rating
4.8
Spread
4
15
Rating
4.8
Spread

57.Clear Rune
57.Clear Rune
Quality 2
Secret Room
Activated
Crane Game
3
15
Rating
7.3
Spread
3
15
Rating
7.3
Spread

58.Black Lotus
58.Black Lotus
Quality 2
Passive
Secret Room
4
12
Rating
5.2
Spread
4
12
Rating
5.2
Spread

59.Missing Page 2
59.Missing Page 2
Passive
Quality 0
Secret Room
Devil Beggar
Devil Room
6
6
Rating
2.4
Spread
6
6
Rating
2.4
Spread

60.Key Bum
60.Key Bum
Passive
Baby Shop
Treasure Room
Quality 0
Secret Room
Key Master
3
3
Rating
1.9
Spread
3
3
Rating
1.9
Spread

61.Wavy Cap
61.Wavy Cap
Quality 1
Secret Room
Activated
4
3
Rating
1.8
Spread
4
3
Rating
1.8
Spread

62.Strawman
62.Strawman
Quality 2
Passive
Secret Room
4
2
Rating
1.1
Spread
4
2
Rating
1.1
Spread

63.Keeper's Kin
63.Keeper's Kin
Quality 2
Passive
Treasure Room
Secret Room
2
2
Rating
2.6
Spread
2
2
Rating
2.6
Spread

64.The Necronomicon
64.The Necronomicon
Quality 1
Secret Room
Activated
Library
Devil Room
6
2
Rating
0.6
Spread
6
2
Rating
0.6
Spread

65.TMTRAINER
65.TMTRAINER
Passive
Quality 0
Secret Room
4
1
Rating
1
Spread
4
1
Rating
1
Spread

66.GB Bug
66.GB Bug
Passive
Quality 1
Treasure Room
Secret Room
3
0
Rating
2.5
Spread
3
0
Rating
2.5
Spread