The Binding of Isaac Items Tier List

S

A

B

C

D

F

S Tier

Death Certificate, Sacred Heart, Glitched Crown

A Tier

C Section, Twisted Pair, R Key, Sacred Orb, The D6, Godhead, Mom's Knife, Holy Mantle, Spindown Dice, Brimstone, Tech X, D Infinity, Incubus, Psy Fly, Cricket's Head, Magic Mushroom, Rock Bottom, Jacob's Ladder, A Lump of Coal, Crown of Light, Goat Head, Trisagion, Mutant Spider, The Parasite, Diplopia, Red Key, The Wafer, Birthright, More Options, Holy Light, Stop Watch, Ceremonial Robes, Ghost Pepper, Pyromaniac, Chaos, Revelation, Succubus, The Stairway, Technology, 20/20, Dead Eye, Spoon Bender, Apple!, Technology Zero, Athame, The Mark, Mystery Gift, Mega Mush, Tractor Beam, Immaculate Heart, Eye of Belial, Polyphemus, Spirit Sword, Eternal D6, Abaddon, Haemolacria, Cricket's Body, The Pact, Backstabber, Binge Eater, Flip, Host Hat, 8 Inch Nails, Death's Touch, Blood of the Martyr, Tough Love, Lusty Blood, Pluto, Bird's Eye, Eucharist, Sausage, Explosivo, Dogma (Item), The Halo, Maw of the Void, Rotten Baby, Rubber Cement, Book of Revelations, Bag of Crafting, SMB Super Fan, Black Candle, Gnawed Leaf, Cancer, Tech.5, Star of Bethlehem, YO LISTEN!, Squeezy, Fruit Cake, Dead Cat, The Mind, Dead Dove, Terra, Daddy Longlegs, Pentagram, Guppy's Eye, Capricorn, Growth Hormones, Head of the Keeper, Ocular Rift, Fire Mind

B Tier

Monstro's Lung, Genesis, Steam Sale, Mucormycosis, Dark Matter, The Small Rock, Paschal Candle, Money = Power, The Battery, Technology 2, The Inner Eye, The Soul, Binky, Lachryphagy, Guppy's Tail, Little Horn (Item), Damocles, Proptosis, Ipecac, Libra, Purity, Wire Coat Hanger, Book of Virtues, My Reflection, Lord of the Pit, Forget Me Now, Holy Grail, Blue Map, Cat-O-Nine-Tails, Eye of the Occult, Eden's Blessing, Lost Contact, Mom's Contacts, Lemegeton, Member Card, Stigmata, Toxic Shock, Angelic Prism, PHD, Seraphim, Stapler, Voodoo Head, Habit, Mr. Dolly, Synthoil, Mama Mega!, Bot Fly, Lil Brimstone, Restock, Eve's Mascara, Car Battery, Uranus, Humbleing Bundle, Lucky Foot, The Sad Onion, Dog Tooth, Rosary, A Dollar, Red Stew, Lodestone, Infestation 2, Sack Head, Sulfuric Acid, Odd Mushroom (Large), Satanic Bible, Infamy, Continuum, Worm Friend, Knockout Drops, Duality, Euthanasia, Lil Dumpy, Camo Undies, Spirit of the Night, The Intruder, 9 Volt, Sulfur, PJs, Champion Belt, Dark Arts, 4.5 Volt, Sagittarius, Book of Shadows, Roid Rage, X-Ray Vision, Lil Abaddon, Soy Milk, 1up!, Black Lotus, Flat Stone, Act of Contrition, Rune Bag, We Need to Go Deeper!, Lead Pencil, Blue Cap, Placenta, Chocolate Milk, Neptunus, Blanket, Gello, Tooth Picks, Divorce Papers, Scorpio, A Bar of Soap, Mom's Key, Pyro, Dark Bum, Eden's Soul, Saturnus, Mysterious Liquid, There's Options, Blank Card, Ouija Board, Dead Onion, The Body, Salvation, Parasitoid, Mom's Pearls, Playdough Cookie, Whore of Babylon, Epic Fetus, Judas' Shadow, Compound Fracture, 3 Dollar Bill, Sinus Infection, Schoolbag, Guppy's Paw, Scapular, Echo Chamber, Options?, 7 Seals, Void, Mitre, Transcendence, Crystal Ball, Monstrance, Mom's Ring, Gimpy, Sharp Plug, Alabaster Box, BFFS!, Censer, The Ludovico Technique, Leech, Contagion, Cupid's Arrow, Treasure Map, Holy Water, Urn of Souls, Dr. Fetus, Torn Photo, Jumper Cables, Charged Baby, Serpent's Kiss, Charm of the Vampire, Keeper's Sack, Freezer Baby, Eye Drops, Guppy's Collar, Coupon, The Mulligan, Fate, Virgo, The Relic, Brittle Bones, Tarot Cloth, Trinity Shield, Abyss, Sacrificial Altar, Mini Mush, Guppy's Head, Sacrificial Dagger, False PHD, Skeleton Key, Odd Mushroom (Thin), Pisces, Glass Eye, Dad's Ring, Almond Milk, Tropicamide, Divine Intervention, Analog Stick, Pop!, Raw Liver, Sol, The Book of Belial, Mega Blast, Marbles, Fanny Pack, A Pony, The Polaroid, Spider Mod, Consolation Prize, D20

C Tier

Luna, Magic Scab, Mr. ME!, Crooked Penny, Dry Baby, Bozo, Box of Friends, Broken Modem, 120 Volt, Steven (Item), MEAT!, Blood Bag, Prayer Card, White Pony, Orphan Socks, Bloody Lust, Cube of Meat, Hungry Soul, Mom's Eye, Cambion Conception, Book of the Dead, Kidney Stone, Spelunker Hat, Pupula Duplex, Glitter Bombs, Magic 8 Ball, The Compass, Quints, Jesus Juice, Starter Deck, Black Hole, Adrenaline, Aquarius, Old Bandage, Glowing Hourglass, Mars, Suplex!, Book of Secrets, Cain's Other Eye, Redemption, Little Steven, Buddy in a Box, Astral Projection, The Negative, Chemical Peel, D100, Tammy's Head, Contract From Below, Speed Ball, Cone Head, Multidimensional Baby, Maggy's Bow, Tooth and Nail, Lil Loki, Mongo Baby, Lil Monstro, Mom's Perfume, Blood Clot, Rotten Tomato, Yum Heart, Midas' Touch, Inner Child, Ghost Bombs, Soul Locket, The Bible, Scatter Bombs, Screw, Bloody Gust, Sissy Longlegs, Clear Rune, Iron Bar, Death's List, Metal Plate, The Nail, The Peeper, Loki's Horns, Dream Catcher, Moving Box, Everything Jar, Belly Button, Card Reading, Dad's Key, Butt Bombs, Mom's Purse, Deep Pockets, Anti-Gravity, Ankh, Gemini (Item), Evil Charm, Pandora's Box, Rainbow Baby, The Swarm, Anemic, Mercurius, Smart Fly, Purgatory, The Common Cold, D1, Big Fan, Caffeine Pill, Fruity Plum, Super Bandage, Evil Eye, Halo of Flies, Telepathy for Dummies, Brother Bobby, Tiny Planet, Spider Bite, Mr. Mega, Montezuma's Revenge, Harlequin Baby, Aries, Acid Baby, Spear of Destiny, Azazel's Rage, Hive Mind, Wooden Nickel, Latch Key, Marrow, Spiderbaby, Robo-Baby, Dad's Lost Coin, Robo-Baby 2.0, Belly Jelly, The Ladder, Bomber Boy, Lil Portal, Boom!, Boiled Baby, Demon Baby, Immaculate Conception, Glyph of Balance, Hallowed Ground, Anima Sola, Empty Vessel, Rocket in a Jar, Lunch, The Book of Sin, Spirit Shackles, Sworn Protector, Magic Skin, Brimstone Bombs, Sack of Pennies, Stem Cells, Sad Bombs, Circle of Protection, Bogo Bombs, Fate's Reward, Smelter, Shoop Da Whoop!, Mystery Sack, Papa Fly, King Baby, Stye, Distant Admiration, Taurus, Sticky Bombs, Plum Flute, Dark Prince's Crown, Finger!, Greed's Gullet, Epiphora, Skatole, Lil Chest, Juicy Sack, Ghost Baby, Guardian Angel, Guppy's Hair Ball, Little C.H.A.D., Vengeful Spirit, Zodiac, Stitches, Lost Soul, Number One, BBF, Cube Baby, Black Powder, Breakfast, Lil Gurdy, Large Zit, No. 2, Isaac's Tomb, Deck of Cards, ???'s Only Friend, Dead Bird, Polydactyly, Bursting Sack, Blood Bombs, Vade Retro, Lazarus' Rags, Eye of Greed, Vanishing Twin, Cracked Orb, The Candle, Jupiter, Sack of Sacks, A Quarter, Key Piece 1, Box of Spiders, Celtic Cross, Monster Manual, Safety Pin, Abel, Recall, Wooden Spoon, Telekinesis, The Virus, Venus, Decap Attack, Lil Delirium, Pageant Boy, Bum Friend, Hot Bombs, Berserk!, Hypercoagulation, Teleport 2.0, Ball of Bandages, Piggy Bank, Mom's Eyeshadow, Headless Baby, Box, Bone Spurs, Lost Fly, The Belt, Varicose Veins, Giant Cell

D Tier

Larynx, Midnight Snack, Vasculitis, Bloodshot Eye, Lil Haunt, A Snack, Betrayal, Bobby-Bomb, Booster Pack (Item), Isaac's Tears, Fast Bombs, Bob's Brain, Match Book, Isaac's Heart, Red Candle, Placebo, Sister Maggy, Bob's Curse, My Little Unicorn, 2Spooky, Eye Sore, Jar of Wisps, Esau Jr., D4, Crack the Sky, Fortune Cookie, IV Bag, God's Flesh, Thunder Thighs, Crack Jacks, Notched Axe, D8, Friend Zone, How to Jump, Dull Razor, Leo, It Hurts, Dead Tooth, Potato Peeler, Experimental Treatment, Mom's Lipstick, My Shadow, Sanguine Bond, Head of Krampus, Magic Fingers, Best Bud, Guillotine, Ball of Tar, D7, The Necronomicon, Little Chubby, Mom's Box, Glass Cannon, The Hourglass, Hushy, Mom's Coin Purse, Dinner, Breath of Life, Bucket of Lard, Obsessed Fan, Eraser, Little Gish, Rotten Meat, Heartbreak, Broken Watch, Mom's Wig, Wavy Cap, Milk!, Bomb Bag, Friend Finder, <3, Night Light, Sumptorium, Jaw Bone, Tinytoma, Sprinkler, Dirty Mind, Depression, Nancy Bombs, Sharp Straw, Ventricle Razor, Mystery Egg, Keeper's Box, Mom's Bottle of Pills, Scissors, Strange Attractor, Akeldama, Friendly Ball, Mom's Razor, Unicorn Stump, Bird Cage, Key Bum, Lemon Mishap, Supper, A Pound of Flesh, Slipped Rib, Linger Bean, The Pinking Shears, Battery Pack, The Gamekid, Angry Fly, Hemoptysis, Delirious, Candy Heart, Farting Baby, Key Piece 2, Portable Slot, The Boomerang, Strawman, Missing Page 2, Plan C, IBS, Poke Go, Mr. Boom, Converter, Glaucoma, Pointy Rib, GB Bug, Samson's Chains, Undefined, Pay to Play, Infestation, Cursed Eye, Blood Oath, Empty Heart, Free Lemonade, Forever Alone, Shade, Flush!, Spider Butt, E. Coli, Mine Crafter, The Jar, Dessert, Metronome, Lil Spewer, Teleport!, Punching Bag, Big Chubby, Magneto, Little Baggy, Marked, Leprosy, The Scooper, Wait What?, Mom's Underwear, Mom's Bracelet, Doctor's Remote, Best Friend, Dad's Note, Yuck Heart, Mom's Shovel, Remote Detonator, The Poop, Missing No., Mega Bean, Mom's Heels, Meat Cleaver, Dead Sea Scrolls, Shard of Glass, Razor Blade, The Wiz, Clicker, Mom's Bra, Hold, Knife Piece 2, Blood Puppy, TMTRAINER, Tonsil, Anarchist Cookbook, Blood Rights, Keeper's Kin, Monstro's Tooth, Bumbo, Compost, Jar of Flies, Brown Nugget, Sharp Key, Bob's Rotten Head, Curse of the Tower, Kamikaze!, The Bean, Tear Detonator, Dataminer, Spin to Win, D10, Butter Bean, D12, Broken Shovel, Pause, Knife Piece 1, Broken Glass Cannon, Golden Razor, Kidney Bean

F Tier

The Black Bean, Mom's Pad