The Best Activated Items

A list of all activated items from The Binding of Isaac: Rebirth, ranked from best to worst. We combined votes from 28 players to create this list. Based on the latest version of The Binding of Isaac: Repentance.

70 Items

342 Votes

28 Voters

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1.D1
1.D1
Quality 2
Treasure Room
Activated
Crane Game
1
100
Rating
0
Spread
1
100
Rating
0
Spread

1.D4
1.D4
Quality 2
Treasure Room
Activated
Crane Game
1
100
Rating
0
Spread
1
100
Rating
0
Spread

1.Genesis
1.Genesis
Angel Room
Quality 3
Activated
1
100
Rating
0
Spread
1
100
Rating
0
Spread

1.Flush!
1.Flush!
Quality 1
Treasure Room
Activated
1
100
Rating
0
Spread
1
100
Rating
0
Spread

1.Dull Razor
1.Dull Razor
Quality 1
Activated
Shop
1
100
Rating
0
Spread
1
100
Rating
0
Spread

1.The Nail
1.The Nail
Quality 2
Activated
Devil Beggar
Devil Room
1
100
Rating
0
Spread
1
100
Rating
0
Spread

7.Death Certificate
7.Death Certificate
Secret Room
Quality 4
Activated
21
96
Rating
0.4
Spread
21
96
Rating
0.4
Spread

8.R Key
8.R Key
Secret Room
Quality 4
Activated
21
94
Rating
0.3
Spread
21
94
Rating
0.3
Spread

9.The Scooper
9.The Scooper
Quality 1
Treasure Room
Activated
1
89
Rating
0
Spread
1
89
Rating
0
Spread

10.Mom's Bottle of Pills
10.Mom's Bottle of Pills
Quality 1
Treasure Room
Old Chest
Beggar
Activated
Devil Beggar
Crane Game
Shop
1
86
Rating
0
Spread
1
86
Rating
0
Spread

10.My Little Unicorn
10.My Little Unicorn
Quality 1
Treasure Room
Activated
Crane Game
1
86
Rating
0
Spread
1
86
Rating
0
Spread

12.Larynx
12.Larynx
Quality 2
Treasure Room
Activated
1
80
Rating
0
Spread
1
80
Rating
0
Spread

13.Ventricle Razor
13.Ventricle Razor
Quality 1
Activated
Shop
1
78
Rating
0
Spread
1
78
Rating
0
Spread

14.Free Lemonade
14.Free Lemonade
Quality 1
Treasure Room
Activated
1
75
Rating
0
Spread
1
75
Rating
0
Spread

14.The Book of Sin
14.The Book of Sin
Quality 2
Treasure Room
Activated
Library
Devil Room
1
75
Rating
0
Spread
1
75
Rating
0
Spread

14.Lemon Mishap
14.Lemon Mishap
Treasure Room
Quality 0
Activated
1
75
Rating
0
Spread
1
75
Rating
0
Spread

14.Red Key
14.Red Key
Quality 3
Ultra Secret Room
Secret Room
Activated
Key Master
Curse Room
Red Chest
1
75
Rating
0
Spread
1
75
Rating
0
Spread

18.The D6
18.The D6
Ultra Secret Room
Treasure Room
Quality 4
Activated
Crane Game
22
75
Rating
0.9
Spread
22
75
Rating
0.9
Spread

19.Spindown Dice
19.Spindown Dice
Treasure Room
Secret Room
Quality 4
Activated
Crane Game
22
75
Rating
0.9
Spread
22
75
Rating
0.9
Spread

20.D100
20.D100
Quality 3
Treasure Room
Activated
Crane Game
1
67
Rating
0
Spread
1
67
Rating
0
Spread

20.Yuck Heart
20.Yuck Heart
Quality 1
Treasure Room
Activated
Rotten Beggar
1
67
Rating
0
Spread
1
67
Rating
0
Spread

22.Magic Fingers
22.Magic Fingers
Quality 1
Treasure Room
Activated
Shop
2
64
Rating
25
Spread
2
64
Rating
25
Spread

23.D Infinity
23.D Infinity
Treasure Room
Secret Room
Quality 4
Activated
24
63
Rating
1.1
Spread
24
63
Rating
1.1
Spread

24.Monster Manual
24.Monster Manual
Quality 1
Treasure Room
Activated
Library
Devil Room
2
63
Rating
34.2
Spread
2
63
Rating
34.2
Spread

25.Crooked Penny
25.Crooked Penny
Quality 2
Treasure Room
Beggar
Activated
Shop
1
60
Rating
0
Spread
1
60
Rating
0
Spread

26.Forget Me Now
26.Forget Me Now
Quality 3
Treasure Room
Secret Room
Activated
Devil Beggar
Devil Room
2
59
Rating
2.5
Spread
2
59
Rating
2.5
Spread

27.Wait What?
27.Wait What?
Quality 1
Treasure Room
Activated
1
58
Rating
0
Spread
1
58
Rating
0
Spread

28.Mom's Bra
28.Mom's Bra
Quality 1
Treasure Room
Old Chest
Activated
2
54
Rating
31.9
Spread
2
54
Rating
31.9
Spread

29.D7
29.D7
Quality 1
Treasure Room
Activated
Crane Game
2
53
Rating
8.8
Spread
2
53
Rating
8.8
Spread

30.Eden's Soul
30.Eden's Soul
Angel Room
Quality 3
Activated
1
50
Rating
0
Spread
1
50
Rating
0
Spread

30.Meat Cleaver
30.Meat Cleaver
Quality 1
Treasure Room
Activated
1
50
Rating
0
Spread
1
50
Rating
0
Spread

30.Keeper's Box
30.Keeper's Box
Quality 2
Secret Room
Activated
Wooden Chest
Shop
1
50
Rating
0
Spread
1
50
Rating
0
Spread

30.Mom's Box
30.Mom's Box
Quality 2
Old Chest
Activated
Crane Game
Wooden Chest
Shop
1
50
Rating
0
Spread
1
50
Rating
0
Spread

30.Clear Rune
30.Clear Rune
Quality 2
Secret Room
Activated
Crane Game
1
50
Rating
0
Spread
1
50
Rating
0
Spread

30.Eternal D6
30.Eternal D6
Quality 3
Treasure Room
Secret Room
Activated
Crane Game
1
50
Rating
0
Spread
1
50
Rating
0
Spread

36.Mega Mush
36.Mega Mush
Treasure Room
Secret Room
Quality 4
Activated
24
50
Rating
0.8
Spread
24
50
Rating
0.8
Spread

37.Doctor's Remote
37.Doctor's Remote
Quality 1
Treasure Room
Activated
Crane Game
1
44
Rating
0
Spread
1
44
Rating
0
Spread

38.Mr. Boom
38.Mr. Boom
Quality 1
Treasure Room
Bomb Bum
Activated
2
44
Rating
5.6
Spread
2
44
Rating
5.6
Spread

39.Satanic Bible
39.Satanic Bible
Treasure Room
Quality 4
Activated
Library
Devil Room
20
41
Rating
0.9
Spread
20
41
Rating
0.9
Spread

40.Flip
40.Flip
Ultra Secret Room
Secret Room
Quality 4
Activated
Curse Room
21
41
Rating
1.3
Spread
21
41
Rating
1.3
Spread

41.Mega Blast
41.Mega Blast
Quality 4
Activated
Devil Room
19
39
Rating
0.8
Spread
19
39
Rating
0.8
Spread

42.Blank Card
42.Blank Card
Quality 2
Treasure Room
Secret Room
Activated
Shop
1
38
Rating
0
Spread
1
38
Rating
0
Spread

42.Book of Secrets
42.Book of Secrets
Quality 1
Treasure Room
Secret Room
Activated
Library
1
38
Rating
0
Spread
1
38
Rating
0
Spread

44.Vade Retro
44.Vade Retro
Quality 2
Angel Room
Activated
1
33
Rating
0
Spread
1
33
Rating
0
Spread

44.Monstro's Tooth
44.Monstro's Tooth
Quality 1
Treasure Room
Activated
1
33
Rating
0
Spread
1
33
Rating
0
Spread

44.The Pinking Shears
44.The Pinking Shears
Quality 2
Treasure Room
Activated
1
33
Rating
0
Spread
1
33
Rating
0
Spread

44.The Candle
44.The Candle
Quality 2
Activated
Shop
1
33
Rating
0
Spread
1
33
Rating
0
Spread

48.Void
48.Void
Angel Room
Quality 4
Activated
Devil Room
21
33
Rating
1.1
Spread
21
33
Rating
1.1
Spread

49.Abyss
49.Abyss
Ultra Secret Room
Quality 4
Activated
Devil Room
21
27
Rating
1
Spread
21
27
Rating
1
Spread

50.We Need to Go Deeper!
50.We Need to Go Deeper!
Quality 2
Secret Room
Activated
Devil Room
1
25
Rating
0
Spread
1
25
Rating
0
Spread

50.Glass Cannon
50.Glass Cannon
Quality 1
Treasure Room
Activated
Crane Game
1
25
Rating
0
Spread
1
25
Rating
0
Spread

50.Placebo
50.Placebo
Quality 2
Secret Room
Activated
Shop
1
25
Rating
0
Spread
1
25
Rating
0
Spread

53.The Book of Belial
53.The Book of Belial
Quality 2
Activated
Library
Devil Room
3
23
Rating
6.3
Spread
3
23
Rating
6.3
Spread

54.Mom's Bracelet
54.Mom's Bracelet
Quality 1
Old Chest
Activated
Crane Game
Shop
1
20
Rating
0
Spread
1
20
Rating
0
Spread

55.The Necronomicon
55.The Necronomicon
Quality 1
Secret Room
Activated
Library
Devil Room
2
16
Rating
13.9
Spread
2
16
Rating
13.9
Spread

56.Wavy Cap
56.Wavy Cap
Quality 1
Secret Room
Activated
2
10
Rating
5.8
Spread
2
10
Rating
5.8
Spread

57.Head of Krampus
57.Head of Krampus
Quality 2
Activated
1
8
Rating
0
Spread
1
8
Rating
0
Spread

58.Mom's Shovel
58.Mom's Shovel
Quality 4
Activated
19
5
Rating
0.3
Spread
19
5
Rating
0.3
Spread

59.Broken Shovel
59.Broken Shovel
Quality 4
Activated
20
1
Rating
0.1
Spread
20
1
Rating
0.1
Spread

60.Mom's Pad
60.Mom's Pad
Treasure Room
Old Chest
Quality 0
Activated
1
0
Rating
0
Spread
1
0
Rating
0
Spread

60.Esau Jr.
60.Esau Jr.
Quality 2
Ultra Secret Room
Treasure Room
Secret Room
Activated
1
0
Rating
0
Spread
1
0
Rating
0
Spread

60.The Poop
60.The Poop
Treasure Room
Quality 0
Activated
Shell Game
1
0
Rating
0
Spread
1
0
Rating
0
Spread

60.Compost
60.Compost
Quality 1
Secret Room
Activated
Shop
Rotten Beggar
1
0
Rating
0
Spread
1
0
Rating
0
Spread

60.Delirious
60.Delirious
Angel Room
Quality 1
Activated
1
0
Rating
0
Spread
1
0
Rating
0
Spread

60.Alabaster Box
60.Alabaster Box
Quality 2
Activated
Shop
1
0
Rating
0
Spread
1
0
Rating
0
Spread

60.Dead Sea Scrolls
60.Dead Sea Scrolls
Angel Room
Quality 1
Treasure Room
Activated
1
0
Rating
0
Spread
1
0
Rating
0
Spread

60.Notched Axe
60.Notched Axe
Quality 1
Treasure Room
Activated
Crane Game
Shop
1
0
Rating
0
Spread
1
0
Rating
0
Spread

60.Razor Blade
60.Razor Blade
Treasure Room
Quality 0
Activated
Devil Beggar
Curse Room
Devil Room
1
0
Rating
0
Spread
1
0
Rating
0
Spread

60.Plan C
60.Plan C
Ultra Secret Room
Quality 0
Activated
Devil Beggar
Curse Room
Red Chest
Shop
Devil Room
1
0
Rating
0
Spread
1
0
Rating
0
Spread

60.D10
60.D10
Quality 1
Treasure Room
Activated
Crane Game
1
0
Rating
0
Spread
1
0
Rating
0
Spread