The Best Activated Items

A list of all activated items from The Binding of Isaac: Rebirth, ranked from best to worst. We combined votes from 35 players to create this list. Based on the latest version of The Binding of Isaac: Repentance.

72 Items

414 Votes

35 Voters

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1.D1
1.D1
Quality 2
Treasure Room
Activated
Crane Game
1
100
Rating
0
Spread
1
100
Rating
0
Spread

1.D4
1.D4
Quality 2
Treasure Room
Activated
Crane Game
1
100
Rating
0
Spread
1
100
Rating
0
Spread

1.Book of Virtues
1.Book of Virtues
Angel Room
Quality 3
Activated
Library
1
100
Rating
0
Spread
1
100
Rating
0
Spread

1.Flush!
1.Flush!
Quality 1
Treasure Room
Activated
1
100
Rating
0
Spread
1
100
Rating
0
Spread

1.Dull Razor
1.Dull Razor
Quality 1
Activated
Shop
1
100
Rating
0
Spread
1
100
Rating
0
Spread

1.The Nail
1.The Nail
Quality 2
Activated
Devil Beggar
Devil Room
1
100
Rating
0
Spread
1
100
Rating
0
Spread

7.Death Certificate
7.Death Certificate
Secret Room
Quality 4
Activated
26
96
Rating
0.3
Spread
26
96
Rating
0.3
Spread

8.R Key
8.R Key
Secret Room
Quality 4
Activated
26
92
Rating
0.4
Spread
26
92
Rating
0.4
Spread

9.The Scooper
9.The Scooper
Quality 1
Treasure Room
Activated
1
89
Rating
0
Spread
1
89
Rating
0
Spread

10.Mom's Bottle of Pills
10.Mom's Bottle of Pills
Quality 1
Treasure Room
Old Chest
Beggar
Activated
Devil Beggar
Crane Game
Shop
1
86
Rating
0
Spread
1
86
Rating
0
Spread

10.My Little Unicorn
10.My Little Unicorn
Quality 1
Treasure Room
Activated
Crane Game
1
86
Rating
0
Spread
1
86
Rating
0
Spread

12.Larynx
12.Larynx
Quality 2
Treasure Room
Activated
1
80
Rating
0
Spread
1
80
Rating
0
Spread

13.Ventricle Razor
13.Ventricle Razor
Quality 1
Activated
Shop
1
78
Rating
0
Spread
1
78
Rating
0
Spread

14.The D6
14.The D6
Ultra Secret Room
Treasure Room
Quality 4
Activated
Crane Game
28
76
Rating
0.7
Spread
28
76
Rating
0.7
Spread

15.Free Lemonade
15.Free Lemonade
Quality 1
Treasure Room
Activated
1
75
Rating
0
Spread
1
75
Rating
0
Spread

15.The Book of Sin
15.The Book of Sin
Quality 2
Treasure Room
Activated
Library
Devil Room
1
75
Rating
0
Spread
1
75
Rating
0
Spread

15.Lemon Mishap
15.Lemon Mishap
Treasure Room
Quality 0
Activated
1
75
Rating
0
Spread
1
75
Rating
0
Spread

15.Red Key
15.Red Key
Quality 3
Ultra Secret Room
Secret Room
Activated
Key Master
Curse Room
Red Chest
1
75
Rating
0
Spread
1
75
Rating
0
Spread

19.Spindown Dice
19.Spindown Dice
Treasure Room
Secret Room
Quality 4
Activated
Crane Game
27
72
Rating
0.8
Spread
27
72
Rating
0.8
Spread

20.D100
20.D100
Quality 3
Treasure Room
Activated
Crane Game
1
67
Rating
0
Spread
1
67
Rating
0
Spread

20.Yuck Heart
20.Yuck Heart
Quality 1
Treasure Room
Activated
Rotten Beggar
1
67
Rating
0
Spread
1
67
Rating
0
Spread

22.D Infinity
22.D Infinity
Treasure Room
Secret Room
Quality 4
Activated
29
66
Rating
0.9
Spread
29
66
Rating
0.9
Spread

23.Eden's Soul
23.Eden's Soul
Angel Room
Quality 3
Activated
2
66
Rating
8.6
Spread
2
66
Rating
8.6
Spread

24.Magic Fingers
24.Magic Fingers
Quality 1
Treasure Room
Activated
Shop
2
64
Rating
25
Spread
2
64
Rating
25
Spread

25.Monster Manual
25.Monster Manual
Quality 1
Treasure Room
Activated
Library
Devil Room
2
63
Rating
34.2
Spread
2
63
Rating
34.2
Spread

26.Crooked Penny
26.Crooked Penny
Quality 2
Treasure Room
Beggar
Activated
Shop
1
60
Rating
0
Spread
1
60
Rating
0
Spread

27.Forget Me Now
27.Forget Me Now
Quality 3
Treasure Room
Secret Room
Activated
Devil Beggar
Devil Room
2
59
Rating
2.5
Spread
2
59
Rating
2.5
Spread

28.Wait What?
28.Wait What?
Quality 1
Treasure Room
Activated
1
58
Rating
0
Spread
1
58
Rating
0
Spread

29.Mom's Bra
29.Mom's Bra
Quality 1
Treasure Room
Old Chest
Activated
2
54
Rating
31.9
Spread
2
54
Rating
31.9
Spread

30.D7
30.D7
Quality 1
Treasure Room
Activated
Crane Game
2
53
Rating
8.8
Spread
2
53
Rating
8.8
Spread

31.Mega Mush
31.Mega Mush
Treasure Room
Secret Room
Quality 4
Activated
30
51
Rating
0.7
Spread
30
51
Rating
0.7
Spread

32.Clear Rune
32.Clear Rune
Quality 2
Secret Room
Activated
Crane Game
1
50
Rating
0
Spread
1
50
Rating
0
Spread

32.Eternal D6
32.Eternal D6
Quality 3
Treasure Room
Secret Room
Activated
Crane Game
1
50
Rating
0
Spread
1
50
Rating
0
Spread

32.Meat Cleaver
32.Meat Cleaver
Quality 1
Treasure Room
Activated
1
50
Rating
0
Spread
1
50
Rating
0
Spread

32.Book of Revelations
32.Book of Revelations
Angel Room
Quality 3
Treasure Room
Activated
Library
1
50
Rating
0
Spread
1
50
Rating
0
Spread

32.Keeper's Box
32.Keeper's Box
Quality 2
Secret Room
Activated
Wooden Chest
Shop
1
50
Rating
0
Spread
1
50
Rating
0
Spread

32.Mom's Box
32.Mom's Box
Quality 2
Old Chest
Activated
Crane Game
Wooden Chest
Shop
1
50
Rating
0
Spread
1
50
Rating
0
Spread

38.Doctor's Remote
38.Doctor's Remote
Quality 1
Treasure Room
Activated
Crane Game
1
44
Rating
0
Spread
1
44
Rating
0
Spread

39.Mr. Boom
39.Mr. Boom
Quality 1
Treasure Room
Bomb Bum
Activated
2
44
Rating
5.6
Spread
2
44
Rating
5.6
Spread

40.Satanic Bible
40.Satanic Bible
Treasure Room
Quality 4
Activated
Library
Devil Room
25
42
Rating
0.7
Spread
25
42
Rating
0.7
Spread

41.Flip
41.Flip
Ultra Secret Room
Secret Room
Quality 4
Activated
Curse Room
26
42
Rating
1
Spread
26
42
Rating
1
Spread

42.Genesis
42.Genesis
Angel Room
Quality 3
Activated
2
38
Rating
34.2
Spread
2
38
Rating
34.2
Spread

42.Blank Card
42.Blank Card
Quality 2
Treasure Room
Secret Room
Activated
Shop
1
38
Rating
0
Spread
1
38
Rating
0
Spread

42.Book of Secrets
42.Book of Secrets
Quality 1
Treasure Room
Secret Room
Activated
Library
1
38
Rating
0
Spread
1
38
Rating
0
Spread

45.Mega Blast
45.Mega Blast
Quality 4
Activated
Devil Room
23
36
Rating
0.7
Spread
23
36
Rating
0.7
Spread

46.Vade Retro
46.Vade Retro
Quality 2
Angel Room
Activated
1
33
Rating
0
Spread
1
33
Rating
0
Spread

46.The Pinking Shears
46.The Pinking Shears
Quality 2
Treasure Room
Activated
1
33
Rating
0
Spread
1
33
Rating
0
Spread

46.The Candle
46.The Candle
Quality 2
Activated
Shop
1
33
Rating
0
Spread
1
33
Rating
0
Spread

46.Monstro's Tooth
46.Monstro's Tooth
Quality 1
Treasure Room
Activated
1
33
Rating
0
Spread
1
33
Rating
0
Spread

50.Void
50.Void
Angel Room
Quality 4
Activated
Devil Room
26
32
Rating
0.9
Spread
26
32
Rating
0.9
Spread

51.Abyss
51.Abyss
Ultra Secret Room
Quality 4
Activated
Devil Room
27
29
Rating
0.8
Spread
27
29
Rating
0.8
Spread

52.We Need to Go Deeper!
52.We Need to Go Deeper!
Quality 2
Secret Room
Activated
Devil Room
1
25
Rating
0
Spread
1
25
Rating
0
Spread

52.Glass Cannon
52.Glass Cannon
Quality 1
Treasure Room
Activated
Crane Game
1
25
Rating
0
Spread
1
25
Rating
0
Spread

52.Placebo
52.Placebo
Quality 2
Secret Room
Activated
Shop
1
25
Rating
0
Spread
1
25
Rating
0
Spread

55.The Book of Belial
55.The Book of Belial
Quality 2
Activated
Library
Devil Room
3
23
Rating
6.3
Spread
3
23
Rating
6.3
Spread

56.Mom's Bracelet
56.Mom's Bracelet
Quality 1
Old Chest
Activated
Crane Game
Shop
1
20
Rating
0
Spread
1
20
Rating
0
Spread

57.The Necronomicon
57.The Necronomicon
Quality 1
Secret Room
Activated
Library
Devil Room
2
16
Rating
13.9
Spread
2
16
Rating
13.9
Spread

58.Delirious
58.Delirious
Angel Room
Quality 1
Activated
2
11
Rating
8.8
Spread
2
11
Rating
8.8
Spread

59.Wavy Cap
59.Wavy Cap
Quality 1
Secret Room
Activated
2
10
Rating
5.8
Spread
2
10
Rating
5.8
Spread

60.Head of Krampus
60.Head of Krampus
Quality 2
Activated
1
8
Rating
0
Spread
1
8
Rating
0
Spread

61.Mom's Shovel
61.Mom's Shovel
Quality 4
Activated
23
6
Rating
0.3
Spread
23
6
Rating
0.3
Spread

62.Broken Shovel
62.Broken Shovel
Quality 4
Activated
26
1
Rating
0.1
Spread
26
1
Rating
0.1
Spread

63.Alabaster Box
63.Alabaster Box
Quality 2
Activated
Shop
1
0
Rating
0
Spread
1
0
Rating
0
Spread

63.Dead Sea Scrolls
63.Dead Sea Scrolls
Angel Room
Quality 1
Treasure Room
Activated
1
0
Rating
0
Spread
1
0
Rating
0
Spread

63.Mom's Pad
63.Mom's Pad
Treasure Room
Old Chest
Quality 0
Activated
1
0
Rating
0
Spread
1
0
Rating
0
Spread

63.Compost
63.Compost
Quality 1
Secret Room
Activated
Shop
Rotten Beggar
1
0
Rating
0
Spread
1
0
Rating
0
Spread

63.Esau Jr.
63.Esau Jr.
Quality 2
Ultra Secret Room
Treasure Room
Secret Room
Activated
1
0
Rating
0
Spread
1
0
Rating
0
Spread

63.The Poop
63.The Poop
Treasure Room
Quality 0
Activated
Shell Game
1
0
Rating
0
Spread
1
0
Rating
0
Spread

63.Notched Axe
63.Notched Axe
Quality 1
Treasure Room
Activated
Crane Game
Shop
1
0
Rating
0
Spread
1
0
Rating
0
Spread

63.Razor Blade
63.Razor Blade
Treasure Room
Quality 0
Activated
Devil Beggar
Curse Room
Devil Room
1
0
Rating
0
Spread
1
0
Rating
0
Spread

63.D10
63.D10
Quality 1
Treasure Room
Activated
Crane Game
1
0
Rating
0
Spread
1
0
Rating
0
Spread

63.Plan C
63.Plan C
Ultra Secret Room
Quality 0
Activated
Devil Beggar
Curse Room
Red Chest
Shop
Devil Room
1
0
Rating
0
Spread
1
0
Rating
0
Spread