The Best Activated Items

A list of all activated items from The Binding of Isaac: Rebirth, ranked from best to worst. We combined votes from 52 players to create this list. Based on the latest version of The Binding of Isaac: Repentance.

73 Items

640 Votes

52 Voters

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All 73 Activated Items Ranked, Best to Worst | The Binding of Isaac | Unduel

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1.Death Certificate
1.Death Certificate
Secret Room
Quality 4
Activated
38
100
Rating
0
Spread
38
100
Rating
0
Spread

2.Red Key
2.Red Key
Quality 3
Ultra Secret Room
Secret Room
Activated
Key Master
Curse Room
Red Chest
2
92
Rating
0.7
Spread
2
92
Rating
0.7
Spread

3.The D6
3.The D6
Ultra Secret Room
Treasure Room
Quality 4
Activated
Crane Game
38
90
Rating
0.1
Spread
38
90
Rating
0.1
Spread

4.Spindown Dice
4.Spindown Dice
Treasure Room
Secret Room
Quality 4
Activated
Crane Game
38
90
Rating
0.1
Spread
38
90
Rating
0.1
Spread

5.Genesis
5.Genesis
Angel Room
Quality 3
Activated
3
88
Rating
6.9
Spread
3
88
Rating
6.9
Spread

6.R Key
6.R Key
Secret Room
Quality 4
Activated
39
88
Rating
0.3
Spread
39
88
Rating
0.3
Spread

7.Crooked Penny
7.Crooked Penny
Quality 2
Treasure Room
Beggar
Activated
Shop
3
88
Rating
5.7
Spread
3
88
Rating
5.7
Spread

8.Book of Virtues
8.Book of Virtues
Angel Room
Quality 3
Activated
Library
2
87
Rating
2.3
Spread
2
87
Rating
2.3
Spread

9.D Infinity
9.D Infinity
Treasure Room
Secret Room
Quality 4
Activated
39
86
Rating
0.5
Spread
39
86
Rating
0.5
Spread

10.A Pony
10.A Pony
Quality 2
Activated
2
85
Rating
17.2
Spread
2
85
Rating
17.2
Spread

11.Suplex!
11.Suplex!
Quality 2
Treasure Room
Activated
Crane Game
2
83
Rating
0.6
Spread
2
83
Rating
0.6
Spread

12.Eternal D6
12.Eternal D6
Quality 3
Treasure Room
Secret Room
Activated
Crane Game
2
78
Rating
2.6
Spread
2
78
Rating
2.6
Spread

13.Black Hole
13.Black Hole
Quality 1
Treasure Room
Activated
2
75
Rating
14.6
Spread
2
75
Rating
14.6
Spread

14.Yum Heart
14.Yum Heart
Quality 1
Ultra Secret Room
Treasure Room
Activated
2
73
Rating
3.7
Spread
2
73
Rating
3.7
Spread

15.Lemegeton
15.Lemegeton
Quality 3
Activated
Library
Devil Room
2
73
Rating
14.6
Spread
2
73
Rating
14.6
Spread

16.My Little Unicorn
16.My Little Unicorn
Quality 1
Treasure Room
Activated
Crane Game
2
70
Rating
2.1
Spread
2
70
Rating
2.1
Spread

17.Book of Revelations
17.Book of Revelations
Angel Room
Quality 3
Treasure Room
Activated
Library
3
63
Rating
9.2
Spread
3
63
Rating
9.2
Spread

18.Damocles
18.Damocles
Quality 2
Activated
Devil Room
4
61
Rating
4.9
Spread
4
61
Rating
4.9
Spread

19.Blank Card
19.Blank Card
Quality 2
Treasure Room
Secret Room
Activated
Shop
2
61
Rating
0.7
Spread
2
61
Rating
0.7
Spread

20.Mom's Bra
20.Mom's Bra
Quality 1
Treasure Room
Old Chest
Activated
2
61
Rating
29.6
Spread
2
61
Rating
29.6
Spread

21.D7
21.D7
Quality 1
Treasure Room
Activated
Crane Game
2
60
Rating
8.4
Spread
2
60
Rating
8.4
Spread

22.Sulfur
22.Sulfur
Quality 3
Ultra Secret Room
Activated
Devil Room
2
59
Rating
10.3
Spread
2
59
Rating
10.3
Spread

23.Mega Mush
23.Mega Mush
Treasure Room
Secret Room
Quality 4
Activated
40
58
Rating
0.3
Spread
40
58
Rating
0.3
Spread

24.Dark Arts
24.Dark Arts
Quality 2
Ultra Secret Room
Activated
Devil Room
3
58
Rating
1.8
Spread
3
58
Rating
1.8
Spread

25.Flip
25.Flip
Ultra Secret Room
Secret Room
Quality 4
Activated
Curse Room
36
57
Rating
0.4
Spread
36
57
Rating
0.4
Spread

26.IV Bag
26.IV Bag
Quality 1
Ultra Secret Room
Activated
Golden Chest
2
54
Rating
15
Spread
2
54
Rating
15
Spread

27.D4
27.D4
Quality 2
Treasure Room
Activated
Crane Game
2
53
Rating
12.2
Spread
2
53
Rating
12.2
Spread

28.Free Lemonade
28.Free Lemonade
Quality 1
Treasure Room
Activated
2
52
Rating
30.9
Spread
2
52
Rating
30.9
Spread

29.Magic Fingers
29.Magic Fingers
Quality 1
Treasure Room
Activated
Shop
2
50
Rating
28.1
Spread
2
50
Rating
28.1
Spread

30.Keeper's Box
30.Keeper's Box
Quality 2
Secret Room
Activated
Wooden Chest
Shop
3
50
Rating
6.5
Spread
3
50
Rating
6.5
Spread

31.Larynx
31.Larynx
Quality 2
Treasure Room
Activated
2
49
Rating
9.7
Spread
2
49
Rating
9.7
Spread

32.Book of the Dead
32.Book of the Dead
Quality 3
Treasure Room
Activated
Library
Devil Room
2
48
Rating
4.8
Spread
2
48
Rating
4.8
Spread

33.Guppy's Head
33.Guppy's Head
Quality 2
Activated
Curse Room
Red Chest
Devil Room
Golden Chest
3
48
Rating
2.7
Spread
3
48
Rating
2.7
Spread

34.Coupon
34.Coupon
Quality 2
Activated
Shop
2
47
Rating
21.5
Spread
2
47
Rating
21.5
Spread

35.Yuck Heart
35.Yuck Heart
Quality 1
Treasure Room
Activated
Rotten Beggar
3
45
Rating
7.8
Spread
3
45
Rating
7.8
Spread

36.Eden's Soul
36.Eden's Soul
Angel Room
Quality 3
Activated
3
45
Rating
2.8
Spread
3
45
Rating
2.8
Spread

37.We Need to Go Deeper!
37.We Need to Go Deeper!
Quality 2
Secret Room
Activated
Devil Room
3
43
Rating
4.1
Spread
3
43
Rating
4.1
Spread

38.Abyss
38.Abyss
Ultra Secret Room
Quality 4
Activated
Devil Room
38
43
Rating
0.6
Spread
38
43
Rating
0.6
Spread

39.Gello
39.Gello
Quality 3
Ultra Secret Room
Treasure Room
Activated
Devil Room
2
43
Rating
5.1
Spread
2
43
Rating
5.1
Spread

40.Forget Me Now
40.Forget Me Now
Quality 3
Treasure Room
Secret Room
Activated
Devil Beggar
Devil Room
4
42
Rating
3.4
Spread
4
42
Rating
3.4
Spread

41.Satanic Bible
41.Satanic Bible
Treasure Room
Quality 4
Activated
Library
Devil Room
34
41
Rating
0.7
Spread
34
41
Rating
0.7
Spread

42.The Book of Belial
42.The Book of Belial
Quality 2
Activated
Library
Devil Room
5
41
Rating
4
Spread
5
41
Rating
4
Spread

43.Void
43.Void
Angel Room
Quality 4
Activated
Devil Room
36
38
Rating
0.6
Spread
36
38
Rating
0.6
Spread

44.Sharp Straw
44.Sharp Straw
Quality 2
Treasure Room
Activated
2
37
Rating
10.5
Spread
2
37
Rating
10.5
Spread

45.Breath of Life
45.Breath of Life
Angel Room
Quality 1
Activated
2
34
Rating
4.8
Spread
2
34
Rating
4.8
Spread

46.Red Candle
46.Red Candle
Quality 2
Ultra Secret Room
Activated
Shop
2
32
Rating
20.3
Spread
2
32
Rating
20.3
Spread

47.Mega Blast
47.Mega Blast
Quality 4
Activated
Devil Room
33
31
Rating
0.7
Spread
33
31
Rating
0.7
Spread

48.Vade Retro
48.Vade Retro
Quality 2
Angel Room
Activated
2
31
Rating
6.7
Spread
2
31
Rating
6.7
Spread

49.Book of Secrets
49.Book of Secrets
Quality 1
Treasure Room
Secret Room
Activated
Library
2
31
Rating
16.4
Spread
2
31
Rating
16.4
Spread

50.Plan C
50.Plan C
Ultra Secret Room
Quality 0
Activated
Devil Beggar
Curse Room
Red Chest
Shop
Devil Room
4
31
Rating
7.3
Spread
4
31
Rating
7.3
Spread

51.Mom's Box
51.Mom's Box
Quality 2
Old Chest
Activated
Crane Game
Wooden Chest
Shop
2
30
Rating
7.5
Spread
2
30
Rating
7.5
Spread

52.The Nail
52.The Nail
Quality 2
Activated
Devil Beggar
Devil Room
4
29
Rating
9.5
Spread
4
29
Rating
9.5
Spread

53.Eraser
53.Eraser
Quality 2
Activated
Crane Game
Shop
2
28
Rating
7
Spread
2
28
Rating
7
Spread

54.Monster Manual
54.Monster Manual
Quality 1
Treasure Room
Activated
Library
Devil Room
5
27
Rating
3.2
Spread
5
27
Rating
3.2
Spread

55.Compost
55.Compost
Quality 1
Secret Room
Activated
Shop
Rotten Beggar
2
26
Rating
6.8
Spread
2
26
Rating
6.8
Spread

56.Unicorn Stump
56.Unicorn Stump
Quality 1
Treasure Room
Activated
2
25
Rating
0.1
Spread
2
25
Rating
0.1
Spread

57.The Book of Sin
57.The Book of Sin
Quality 2
Treasure Room
Activated
Library
Devil Room
4
25
Rating
5
Spread
4
25
Rating
5
Spread

58.D1
58.D1
Quality 2
Treasure Room
Activated
Crane Game
3
23
Rating
3.1
Spread
3
23
Rating
3.1
Spread

59.Glass Cannon
59.Glass Cannon
Quality 1
Treasure Room
Activated
Crane Game
2
22
Rating
4
Spread
2
22
Rating
4
Spread

60.Meat Cleaver
60.Meat Cleaver
Quality 1
Treasure Room
Activated
2
21
Rating
10.2
Spread
2
21
Rating
10.2
Spread

61.The Scooper
61.The Scooper
Quality 1
Treasure Room
Activated
2
19
Rating
24.1
Spread
2
19
Rating
24.1
Spread

62.Guppy's Paw
62.Guppy's Paw
Quality 3
Activated
Curse Room
Red Chest
Devil Room
5
16
Rating
4.5
Spread
5
16
Rating
4.5
Spread

63.Mom's Pad
63.Mom's Pad
Treasure Room
Old Chest
Quality 0
Activated
4
16
Rating
3
Spread
4
16
Rating
3
Spread

64.Wait What?
64.Wait What?
Quality 1
Treasure Room
Activated
3
13
Rating
11.1
Spread
3
13
Rating
11.1
Spread

65.Mr. Boom
65.Mr. Boom
Quality 1
Treasure Room
Bomb Bum
Activated
3
13
Rating
8.1
Spread
3
13
Rating
8.1
Spread

66.Delirious
66.Delirious
Angel Room
Quality 1
Activated
3
10
Rating
3
Spread
3
10
Rating
3
Spread

67.Razor Blade
67.Razor Blade
Treasure Room
Quality 0
Activated
Devil Beggar
Curse Room
Devil Room
3
9
Rating
2.6
Spread
3
9
Rating
2.6
Spread

68.Clear Rune
68.Clear Rune
Quality 2
Secret Room
Activated
Crane Game
2
9
Rating
4.4
Spread
2
9
Rating
4.4
Spread

69.D10
69.D10
Quality 1
Treasure Room
Activated
Crane Game
2
7
Rating
2.9
Spread
2
7
Rating
2.9
Spread

70.The Necronomicon
70.The Necronomicon
Quality 1
Secret Room
Activated
Library
Devil Room
4
6
Rating
1.6
Spread
4
6
Rating
1.6
Spread

71.Broken Shovel
71.Broken Shovel
Quality 4
Activated
39
4
Rating
0.3
Spread
39
4
Rating
0.3
Spread

72.Mom's Shovel
72.Mom's Shovel
Quality 4
Activated
34
2
Rating
0.3
Spread
34
2
Rating
0.3
Spread

73.Wavy Cap
73.Wavy Cap
Quality 1
Secret Room
Activated
3
0
Rating
1.3
Spread
3
0
Rating
1.3
Spread