The Best Activated Items
A list of all activated items from The Binding of Isaac: Rebirth, ranked from best to worst. We combined votes from 66 players to create this list. Based on the latest version of The Binding of Isaac: Repentance.
Vote Now164 Items
1.1K Â Votes
66 Â Voters
My Votes
Sort by
Rating
1.Diplopia
4100Rating1.8
Spread2.Death Certificate
4999Rating0.3
Spread3.Red Key
3.Red Key
Quality 3Ultra Secret RoomSecret RoomActivatedKey MasterCurse RoomRed Chest498Rating1
Spread498Rating1
Spread4.Book of Revelations
598Rating2.7
Spread5.Crooked Penny
496Rating2.9
Spread6.Lemegeton
496Rating3.8
Spread7.Book of Shadows
292Rating5.2
Spread7.White Pony
292Rating5.2
Spread7.Bag of Crafting
292Rating5.2
Spread10.The D6
4891Rating0.3
Spread11.Eternal D6
490Rating2.4
Spread12.R Key
4990Rating0.4
Spread13.Dark Arts
587Rating4.4
Spread14.Smelter
386Rating13.6
Spread15.Black Hole
486Rating4.2
Spread16.How to Jump
282Rating16.9
Spread17.Gello
481Rating5.6
Spread18.Spindown Dice
5080Rating0.6
Spread19.Genesis
480Rating3.7
Spread20.Eden's Soul
678Rating3.9
Spread21.Mega Bean
278Rating13.4
Spread22.Blank Card
378Rating4.6
Spread23.Box of Friends
378Rating6.9
Spread24.The Candle
375Rating8.6
Spread25.Shoop Da Whoop!
475Rating4.3
Spread26.Yum Heart
374Rating1.2
Spread27.Damocles
674Rating6
Spread28.D Infinity
4974Rating0.8
Spread29.Head of Krampus
373Rating10.6
Spread30.Dad's Key
273Rating28.9
Spread31.We Need to Go Deeper!
673Rating4.7
Spread32.Golden Razor
273Rating1.4
Spread33.Coupon
373Rating3.9
Spread34.Book of Virtues
571Rating6.2
Spread35.Alabaster Box
270Rating10
Spread36.Mystery Gift
269Rating10.4
Spread37.Deck of Cards
368Rating10.2
Spread38.Mega Mush
5167Rating0.5
Spread39.Wooden Nickel
266Rating7.7
Spread40.Sulfur
565Rating6
Spread41.Plan C
41.Plan C
Ultra Secret RoomQuality 0ActivatedDevil BeggarCurse RoomRed ChestShopDevil Room765Rating5.7
Spread765Rating5.7
Spread42.Magic Skin
265Rating20.7
Spread42.The Bible
265Rating20.7
Spread44.IV Bag
463Rating8.1
Spread45.Plum Flute
361Rating13.1
Spread46.Moving Box
259Rating15.6
Spread47.Notched Axe
259Rating8.7
Spread48.Sharp Straw
459Rating8.4
Spread49.Keeper's Box
458Rating3.3
Spread50.Urn of Souls
358Rating19.7
Spread51.A Pony
358Rating10.6
Spread52.Forget Me Now
758Rating4.2
Spread53.The Book of Belial
757Rating3.3
Spread54.Suplex!
457Rating11
Spread55.Guppy's Paw
757Rating5.4
Spread56.Flip
4656Rating0.7
Spread57.Satanic Bible
4556Rating0.7
Spread58.Everything Jar
355Rating17.8
Spread59.Void
4755Rating0.6
Spread60.D1
554Rating7
Spread61.The Nail
753Rating6.6
Spread62.Crack the Sky
352Rating20.2
Spread63.Glowing Hourglass
252Rating30.1
Spread64.Box of Spiders
250Rating9.2
Spread65.Friend Finder
249Rating28.2
Spread65.Anima Sola
249Rating28.2
Spread65.Stitches
249Rating28.2
Spread68.Mega Blast
4348Rating0.9
Spread69.My Little Unicorn
446Rating8.8
Spread70.Magic Fingers
446Rating10.7
Spread71.Berserk!
345Rating15.9
Spread72.Teleport!
345Rating12.8
Spread73.Doctor's Remote
345Rating14.6
Spread74.Larynx
345Rating3.8
Spread75.D7
345Rating3.6
Spread76.Abyss
4945Rating0.7
Spread77.Scissors
344Rating14.5
Spread78.Lemon Mishap
243Rating3.8
Spread79.Clear Rune
443Rating12.3
Spread80.Ventricle Razor
343Rating20
Spread81.Mr. ME!
243Rating5.5
Spread82.Decap Attack
442Rating12.8
Spread83.Pandora's Box
342Rating13.4
Spread84.Crystal Ball
342Rating11.7
Spread85.Book of the Dead
442Rating13
Spread86.The Book of Sin
641Rating4.4
Spread87.Book of Secrets
340Rating3.7
Spread88.Potato Peeler
240Rating34.8
Spread89.Blood Rights
340Rating19
Spread90.Monstro's Tooth
339Rating19.6
Spread91.Best Friend
439Rating12.6
Spread92.Prayer Card
339Rating7.2
Spread93.Dataminer
439Rating6.4
Spread94.Jar of Wisps
338Rating12.7
Spread95.D12
238Rating22
Spread96.Eraser
438Rating12.6
Spread97.The Poop
336Rating12.6
Spread98.Dead Sea Scrolls
236Rating9.9
Spread99.Placebo
336Rating12.6
Spread100.Undefined
336Rating12.9
Spread101.D8
435Rating4.7
Spread102.Wavy Cap
535Rating10.6
Spread103.Spin to Win
234Rating11.4
Spread103.Converter
234Rating11.4
Spread105.Razor Blade
533Rating10.1
Spread106.D4
432Rating6.9
Spread107.The Boomerang
332Rating12.1
Spread108.Remote Detonator
108.Remote Detonator
Quality 1Ultra Secret RoomTreasure RoomBomb BumActivatedCrane GameShop431Rating8.4
Spread431Rating8.4
Spread109.Fortune Cookie
330Rating13
Spread110.Portable Slot
629Rating5.2
Spread111.Mom's Box
426Rating5.5
Spread112.Dull Razor
426Rating6.5
Spread113.Tammy's Head
225Rating14.7
Spread113.Friendly Ball
225Rating14.7
Spread113.Metronome
225Rating14.7
Spread116.Glass Cannon
425Rating5.3
Spread117.Guppy's Head
422Rating7.1
Spread118.Mr. Boom
522Rating4.7
Spread119.Spider Butt
321Rating8.2
Spread120.D10
421Rating5.6
Spread121.Mom's Shovel
4419Rating0.7
Spread122.Isaac's Tears
319Rating11.3
Spread123.Sacrificial Altar
318Rating14.5
Spread124.Monster Manual
615Rating3.2
Spread125.Broken Glass Cannon
414Rating9.5
Spread126.Yuck Heart
513Rating5.1
Spread127.Bob's Rotten Head
312Rating7.8
Spread128.Kidney Bean
412Rating6.7
Spread129.Pause
39Rating7.3
Spread130.Broken Shovel
509Rating0.4
Spread131.Unicorn Stump
48Rating3.5
Spread132.Free Lemonade
38Rating10
Spread133.The Scooper
38Rating9.1
Spread134.Meat Cleaver
47Rating3.7
Spread135.Mom's Pad
66Rating1.8
Spread136.D100
26Rating10.7
Spread137.Mom's Bra
56Rating4.9
Spread138.Flush!
45Rating6.5
Spread139.Telekinesis
35Rating8.8
Spread140.Breath of Life
44Rating3.4
Spread141.Mom's Bottle of Pills
141.Mom's Bottle of Pills
Quality 1Treasure RoomOld ChestBeggarActivatedDevil BeggarCrane GameShop34Rating7
Spread34Rating7
Spread142.Vade Retro
54Rating2.4
Spread143.Wait What?
64Rating2.7
Spread144.Red Candle
43Rating3.7
Spread145.Delirious
63Rating1.2
Spread146.The Pinking Shears
23Rating4.6
Spread147.The Hourglass
42Rating3.9
Spread148.Sprinkler
42Rating2.2
Spread149.Esau Jr.
32Rating3
Spread150.The Necronomicon
72Rating0.7
Spread151.Compost
52Rating1.6
Spread152.Tear Detonator
32Rating2.5
Spread153.Mom's Bracelet
31Rating0.5
Spread154.Butter Bean
20Rating0.5
Spread154.Brown Nugget
20Rating0.5
Spread156.Jar of Flies
30Rating1
Spread157.The Bean
30Rating0.3
Spread158.Anarchist Cookbook
20Rating0.6
Spread158.Kamikaze!
20Rating0.6
Spread158.Clicker
20Rating0.6
Spread158.The Gamekid
20Rating0.6
Spread158.Mine Crafter
20Rating0.6
Spread158.Telepathy for Dummies
20Rating0.6
Spread164.Hold
30Rating0.4
Spread
