Unduel Logo
Make a List

The Best Secret Room Items Ranked List

67 Items1.4K Votes91 Voters
Updated October 11, 2025
Vote Now

A list of all secret room items from The Binding of Isaac: Rebirth, ranked from best to worst.

We combined votes from 91 players to create this list.

Based on the latest version of The Binding of Isaac: Repentance.

Sort by

Filter by

Group by

Vote Now