The Hardest Chapter 1 Bosses Tier List

A list of all bosses from chapter 1 of The Binding of Isaac: Rebirth, ranked from hardest to easiest.

Chapter 1 includes the Basement, the Cellar, and the Burning Basement.

This list is based on the latest version of The Binding of Isaac: Repentance.

Rankings updated July 2, 2025.
Vote Now

17 Enemies

51  Votes

3  Voters


Sort by

Filter by


S
A
B
C
D
F
Vote Now
Edit Votes