A list of all bosses from chapter 2.5 of The Binding of Isaac: Rebirth, ranked from hardest to easiest. Chapter 2.5 includes the Mines and the Ashpit. This list is based on the latest version of The Binding of Isaac: Repentance.
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Tuff Twins
Hornfel
Reap Creep, Singe
The Pile, Great Gideon
The Shell
Clutch