The Hardest Chapter 2.5 Bosses

A list of all bosses from chapter 2.5 of The Binding of Isaac: Rebirth, ranked from hardest to easiest.

Chapter 2.5 includes the Mines and the Ashpit.

This list is based on the latest version of The Binding of Isaac: Repentance.

8 Enemies

32 Votes

4 Voters

Sort by

Filter by

Group by