A list of all bosses from The Binding of Isaac: Rebirth, ranked from hardest to easiest. We combined votes from 23 players to create this list. Based on the latest version of The Binding of Isaac: Repentance.
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Mega Satan, Mother, Delirium, Hush
Dogma, Ultra Greedier, Ultra Greed, The Visage, Bumbino, It Lives, ??? (Boss), The Bloat, Ultra War, Ultra Pestilence, The Lamb, Chimera, The Pile, The Heretic, Satan, The Scourge, Daddy Long Legs, The Adversary, Clutch, Ultra Death
Isaac (Boss), The Beast, Rag Mega, Mom, Mom's Heart, Reap Creep, Pestilence, Colostomia, Min-Min, The Stain, Mask of Infamy, Hornfel, Singe, Gurdy Jr., Triachnid, Rotgut, Death (Boss), Dark One, Sisters Vis, Wormwood, Carrion Queen, Tuff Twins, Monstro II, Conquest, Rag Man, The Cage, Scolex, Ultra Famine, Widow, The Rainmaker
The Fallen, War, The Frail, Mama Gurdy, The Horny Boys, The Forsaken, The Matriarch, The Haunt, The Wretched, Great Gideon, Lil Blub, Clog, Lokii, Famine, Turdlet, Peep, The Gate, Steven, The Siren, Mega Maw, Baby Plum, Dingle, Mr. Fred, Blighted Ovum, Dangle, Mega Fatty, Brownie, The Shell, Gurglings
Turdlings, Little Horn, Fistula, Gish, Gemini, Big Horn, Loki, Chub, The Husk, C.H.A.D., Monstro, Teratoma, Blastocyst, Polycephalus, Pin, The Headless Horseman, Larry Jr., Gurdy
The Hollow, The Duke of Flies
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