A list of all bosses from The Binding of Isaac: Rebirth, ranked from hardest to easiest. We combined votes from 16 players to create this list. Based on the latest version of The Binding of Isaac: Repentance.
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Mega Satan
Delirium, The Visage, Mother, Hush, Dogma, Ultra Greedier, Ultra Greed, Bumbino, The Scourge, The Heretic, Chimera, Ultra War, The Adversary, The Lamb
Ultra Pestilence, Min-Min, Ultra Death, Daddy Long Legs, Clutch, The Bloat, Wormwood, It Lives, Satan, The Pile, The Rainmaker, ??? (Boss), Mask of Infamy, Gurdy Jr., Singe, Rag Mega, Mom, Triachnid, Reap Creep, Hornfel, Pestilence
Colostomia, Dark One, The Stain, Mom's Heart, Sisters Vis, Widow, Mama Gurdy, The Beast, Death (Boss), Tuff Twins, Rag Man, Monstro II, Scolex, Turdlet, Rotgut, Ultra Famine, Isaac (Boss), Great Gideon, Carrion Queen, Conquest, The Gate, The Horny Boys, The Cage, The Wretched, The Haunt, The Frail, C.H.A.D., Peep, Dingle, Mr. Fred
Turdlings, Famine, Steven, Teratoma, War, Dangle, Mega Maw, The Fallen, Mega Fatty, The Siren, Blighted Ovum, Baby Plum, Little Horn, Lokii, Gurglings, Chub, Clog, The Husk, Loki, Gemini, Fistula, The Matriarch, Lil Blub, The Forsaken, Big Horn, The Shell, Brownie, Larry Jr., Gish, Blastocyst, Pin, The Headless Horseman, Monstro, Polycephalus
The Duke of Flies, The Hollow, Gurdy
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