A list of all secret room items from The Binding of Isaac: Rebirth, ranked from best to worst. We combined votes from 64 players to create this list. Based on the latest version of The Binding of Isaac: Repentance.
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Glitched Crown, Death Certificate, Red Key
Chaos, Sausage, Eternal D6, Rock Bottom, Sacred Orb, R Key, Blank Card
Spindown Dice, Echo Chamber, Rune Bag, D Infinity, Odd Mushroom (Large), Pyro, Infamy, We Need to Go Deeper!, Mr. Mega, Dad's Ring, Transcendence
Orphan Socks, Greed's Gullet, 1up!, Sack of Pennies, Lost Contact, Keeper's Box, Mystery Sack, Raw Liver, Forget Me Now, Bomb Bag, Vanishing Twin, Binge Eater, Black Lotus, Mega Mush, Clear Rune, Skeleton Key, Flip, Astral Projection, Odd Mushroom (Thin), Spirit Shackles, Keeper's Sack, Cursed Eye, Cracked Orb, Epic Fetus, Sack Head
Sack of Sacks, Lost Soul, Book of Secrets, Wavy Cap, Strawman, Samson's Chains, Placebo, Eye of Greed, Evil Charm, Inner Child, A Quarter, Isaac's Tomb, Esau Jr., Compost
Missing Page 2, Key Bum, Keeper's Kin, The Necronomicon, TMTRAINER, GB Bug
