A list of all secret room items from The Binding of Isaac: Rebirth, ranked from best to worst.
We combined votes from 86 players to create this list.
Based on the latest version of The Binding of Isaac: Repentance.
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Death Certificate, Glitched Crown
Red Key, Rock Bottom, Sausage, Eternal D6, Chaos, Sacred Orb
Spindown Dice, R Key, Echo Chamber, Blank Card, Lost Contact, Rune Bag, Transcendence, D Infinity, Astral Projection, Pyro, Odd Mushroom (Large), Keeper's Box, Infamy, Vanishing Twin, Mystery Sack
Mr. Mega, Black Lotus, Forget Me Now, Orphan Socks, We Need to Go Deeper!, Dad's Ring, Skeleton Key, Keeper's Sack, Sack of Pennies, Spirit Shackles, Raw Liver, Sack Head, Book of Secrets, Isaac's Tomb, 1up!, Odd Mushroom (Thin), Evil Charm, Binge Eater, Inner Child, Cracked Orb, Eye of Greed, Mega Mush, Missing No., Greed's Gullet
Sack of Sacks, Clear Rune, Wavy Cap, Flip, Cursed Eye, Lost Soul, Bomb Bag, Strawman, A Quarter, Epic Fetus, Samson's Chains, Esau Jr., Placebo, GB Bug, Missing Page 2
Compost, Key Bum, The Necronomicon, Keeper's Kin, TMTRAINER
