A list of all secret room items from The Binding of Isaac: Rebirth, ranked from best to worst.
We combined votes from 113 players to create this list.
Based on the latest version of The Binding of Isaac: Repentance.
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Death Certificate, Glitched Crown
Sacred Orb, R Key, Spindown Dice, D Infinity, Red Key, Rock Bottom, Eternal D6, Chaos, Sausage
Lost Contact, Mega Mush, Flip, Binge Eater, Blank Card, 1up!, Forget Me Now, Infamy, We Need to Go Deeper!, Odd Mushroom (Large), Sack Head, Pyro, Echo Chamber, Astral Projection, Skeleton Key, Keeper's Sack, Black Lotus, Rune Bag, Transcendence
Book of Secrets, Epic Fetus, Dad's Ring, Odd Mushroom (Thin), Orphan Socks, Vanishing Twin, Inner Child, Raw Liver, Evil Charm, Isaac's Tomb, Eye of Greed, Mystery Sack, Greed's Gullet, Clear Rune, Spirit Shackles, Cracked Orb, A Quarter, Sack of Pennies, Mr. Mega
Lost Soul, Sack of Sacks, Placebo, Keeper's Box, Key Bum, Wavy Cap, Esau Jr., Missing No., Cursed Eye, Bomb Bag, Missing Page 2, TMTRAINER, Strawman, Samson's Chains, The Necronomicon, GB Bug, Compost
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