A list of all secret room items from The Binding of Isaac: Rebirth, ranked from best to worst.
We combined votes from 76 players to create this list.
Based on the latest version of The Binding of Isaac: Repentance.
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Death Certificate, Glitched Crown, Red Key
Rock Bottom, Chaos, Eternal D6, Sausage, Sacred Orb
Spindown Dice, R Key, Blank Card, Echo Chamber, D Infinity, Lost Contact, Rune Bag, Transcendence, Keeper's Box, Infamy, Pyro, Vanishing Twin, Astral Projection, Mystery Sack, Mr. Mega
Odd Mushroom (Large), We Need to Go Deeper!, Black Lotus, Raw Liver, Skeleton Key, Dad's Ring, Spirit Shackles, Sack Head, Orphan Socks, Forget Me Now, Sack of Pennies, Keeper's Sack, Isaac's Tomb, Book of Secrets, 1up!, Cracked Orb, Odd Mushroom (Thin), Greed's Gullet, Binge Eater, Evil Charm
Mega Mush, Clear Rune, Inner Child, Eye of Greed, Wavy Cap, Sack of Sacks, Flip, Bomb Bag, Cursed Eye, Strawman, Missing No., Placebo, Esau Jr., Epic Fetus, Lost Soul, A Quarter, Samson's Chains, Missing Page 2, Compost
GB Bug, The Necronomicon, Key Bum, Keeper's Kin, TMTRAINER