A list of all bosses from chapter 2 of The Binding of Isaac: Rebirth, ranked from hardest to easiest.
Chapter 2 includes the Caves, the Catacombs, and the Flooded Caves.
This list is based on the latest version of The Binding of Isaac: Repentance.
Vote Now21 Enemies
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Bumbino
Gurdy Jr., Dark One, Carrion Queen, The Wretched, Mega Fatty
The Frail, Peep, Pestilence, Chub, The Stain, Fistula, The Husk
Big Horn, Rag Mega, Mega Maw
The Forsaken, C.H.A.D.
The Hollow, Gurdy, Polycephalus