The Hardest Chapter 2 Bosses Tier List

A list of all bosses from chapter 2 of The Binding of Isaac: Rebirth, ranked from hardest to easiest.

Chapter 2 includes the Caves, the Catacombs, and the Flooded Caves.

This list is based on the latest version of The Binding of Isaac: Repentance.

21 Enemies

63  Votes

3  Voters

Save Image

---

Ranked List

Sort by

Filter by

---

S

A

B

C

D

F

Related Lists

The Best Binding of Isaac Items

The Best Passive Items

The Best Devil Room Items

The Best Activated Items

The Best Angel Room Items

Vote Now

Edit Votes

Delete Votes

Related Lists

The Best Binding of Isaac Items

The Best Passive Items

The Best Devil Room Items

The Best Activated Items

The Best Angel Room Items